Fibrin Glue-Assisted Repair in Recurrent Retinal Detachment Following Post-Viral Retinitis: A Retrospective Analysis of 12 Cases in HIV-Positive Patients.

IF 2.3 4区医学 Q2 OPHTHALMOLOGY

Seminars in Ophthalmology Pub Date : 2025-08-12 DOI:10.1080/08820538.2025.2547322

Vikas Ambiya, Gaurav Kapoor, Mehak Aggarwal, Vijay K Sharma, Sunandan Bhatta

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引用次数: 0

Abstract

Purpose: To evaluate the anatomical and functional outcomes of fibrin glue application in the surgical management of recurrent rhegmatogenous retinal detachment (RRD) in patients with healed post-viral retinitis and HIV infection.

Methods: A retrospective review was conducted of 40 cases of RRD secondary to viral retinitis in HIV-positive patients. Among these, 12 eyes exhibited recurrent detachment under silicone oil and were managed with silicone oil exchange, using fibrin glue to close persistent retinal breaks. Pre- and postoperative visual acuity, anatomical reattachment, and complications were assessed. The time to fibrin glue resorption and any evidence of epiretinal membrane formation were also recorded.

Results: All 12 cases achieved successful retinal reattachment post fibrin glue application. Silicone oil removal was performed between 3 to 4 months postoperatively. Best corrected visual acuity improved in all eyes (mean preoperative LogMAR VA 1.2 ± 0.13 improved to 0.53 ± 0.13, p < .001). There were no pre-operative or post-operative complications. Nineteen of the total 40 cases required concurrent cataract surgery.

Conclusion: Fibrin glue is a safe and effective adjunct for managing persistent retinal breaks in recurrent RRD under silicone oil in HIV-positive individuals with resolved viral retinitis. It promotes retinal reattachment and improves visual outcomes with minimal complications.

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纤维蛋白胶辅助修复病毒性视网膜炎后复发性视网膜脱离：12例hiv阳性患者的回顾性分析。

目的：评价纤维蛋白胶在病毒性视网膜炎合并HIV感染患者复发性孔源性视网膜脱离（RRD）手术治疗中的解剖和功能效果。方法：对40例hiv阳性患者继发病毒性视网膜炎的RRD进行回顾性分析。其中12只眼在硅油作用下出现复发性脱离，采用硅油交换治疗，用纤维蛋白胶闭合持续性视网膜断裂。评估术前和术后的视力、解剖复位和并发症。同时记录纤维蛋白胶吸收的时间和视网膜前膜形成的证据。结果：12例患者应用纤维蛋白胶后视网膜再植均成功。术后3 ~ 4个月进行硅油去除。所有患者的最佳矫正视力均得到改善（术前平均LogMAR VA从1.2±0.13提高到0.53±0.13,p）。结论：纤维蛋白胶是一种安全有效的辅助药物，用于治疗hiv阳性的病毒性视网膜炎患者硅油下复发性RRD的持续性视网膜断裂。它促进视网膜再附着，以最小的并发症改善视力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Seminars in Ophthalmology offers current, clinically oriented reviews on the diagnosis and treatment of ophthalmic disorders. Each issue focuses on a single topic, with a primary emphasis on appropriate surgical techniques.