David Doubblestein, Deanne Fay, Sarah Brunskill, Betty Westbrook, Brittany Williams
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引用次数: 0
Abstract
Aim: To determine whether a 4-day, twice-daily complete decongestive therapy (CDT) intervention effectively reduces limb volume in pediatric patients with primary and secondary lymphedema. Methods: A retrospective cohort study was conducted using rehabilitation records of children aged 5-17 years from Camp Watchme, a North American summer camp providing lymphedema interventions. Results: Over 4 years, 38 unique campers contributed 66 records for analysis. The majority were female (68.42%), with a mean age of 9.30 ± 2.66 years. Lower extremity limb volume demonstrated statistically significant reductions across all 4 years (2021, p = 0.011; 2022, p = 0.030; 2023, p < 0.001; 2024, p < 0.001). Cumulative analysis of upper extremities (n = 16) also showed significant volume reduction (p = 0.042, r = 0.50). Daily measurement tracking (n = 43) indicated consistent percent volume decreases, with confidence intervals supporting a meaningful change for lower extremity limb volume differences across 4 years. Conclusion: An intensive, short-duration CDT intervention significantly reduces limb volume in pediatric patients with lymphedema. Future research should explore long-term effects, optimize CDT protocols, and assess broader functional and psychosocial outcomes to enhance pediatric lymphedema management.
期刊介绍:
Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology.
Lymphatic Research and Biology coverage includes:
-Vasculogenesis and angiogenesis
-Genetics of lymphatic disorders
-Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies
-Physiology of intestinal fluid and protein balance
-Immunosurveillance and immune cell trafficking
-Tumor biology and metastasis
-Pharmacology
-Lymphatic imaging
-Endothelial and smooth muscle cell biology
-Inflammation, infection, and autoimmune disease