Impact of the COVID-19 pandemic on the incidence and recurrence of central serous chorioretinopathy in Greece: a multicenter study.

IF 1.4 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2025-08-12 DOI:10.1007/s10792-025-03704-1

Alexandros Rouvas, Ioannis Datseris, Ilias Georgalas, Miltiadis Tsilimbaris, Paris Tranos, Panagiotis Theodosiadis, Malvina-Efthimia Tzanidaki, Marina Kardara, Konstantinos Tyrlis, Dimitrios Spyropoulos, Rafaela Datseri, Anastasios Stavrakakis, Marianna Tranou, Pavlina Kazantzidou, Nikolaos Gouliopoulos

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引用次数: 0

Abstract

Purpose: To investigate the impact of the COVID-19 pandemic on the incidence and recurrence of central serous chorioretinopathy (CSCR) in Greece, analyzing data from 2017 to 2023.

Methods: A retrospective, observational, cross-sectional study was conducted, including patients diagnosed with either new-onset or recurrent CSCR at five ophthalmology departments in Greece from January 2017 to December 2023. Data were categorized into "pre-COVID" (2017-2019) and "COVID" (2021-2023) periods, excluding cases from 2020 due to lockdown restrictions. Patient demographics, disease recurrence, and COVID-19 infection history were recorded. Statistical analyses included chi-square tests, Spearman's rank correlation, and Student's t-test.

Results: A total of 730 CSCR cases were analyzed (435 new-onset, 295 recurrent). The participants' mean age was 46.8 ± 7.5 years. The overall number of cases significantly increased during the COVID-19 period (462 cases) compared to the pre-COVID period (268 cases) (p < 0.001). Both new-onset (164 vs. 271, p < 0.001) and recurrent cases (104 vs. 191, p < 0.001) showed a significant rise. Among patients from 2021 to 2023, those with a confirmed COVID-19 infection had significantly higher CSCR rates compared to non-infected individuals (p < 0.001).

Conclusion: The COVID-19 pandemic was associated with a significant increase in CSCR incidence and recurrence in Greece. This rise may be attributed to heightened psychological stress and endogenous cortisol elevation during the pandemic, as well as direct viral effects and corticosteroid use in infected patients. Further studies are needed to explore underlying mechanisms and long-term consequences.

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COVID-19大流行对希腊中枢性浆液性脉络膜视网膜病变发病率和复发的影响：一项多中心研究

目的：分析2017 - 2023年希腊新冠肺炎疫情对中枢性浆液性脉络膜视网膜病变（CSCR）发病率和复发的影响。方法：回顾性、观察性、横断面研究，纳入2017年1月至2023年12月希腊5个眼科诊断为新发或复发性CSCR的患者。数据分为“pre-COVID”（2017-2019）和“COVID”（2021-2023）时期，不包括2020年以来由于封锁限制的病例。记录患者人口统计、疾病复发和COVID-19感染史。统计分析包括卡方检验、Spearman秩相关检验和学生t检验。结果：共分析730例CSCR，其中新发病例435例，复发病例295例。参与者平均年龄46.8±7.5岁。与COVID-19前时期（268例）相比，COVID-19期间总病例数（462例）显著增加(p结论：COVID-19大流行与希腊CSCR发病率和复发率显著增加有关。这一上升可能归因于大流行期间心理压力加剧和内源性皮质醇升高，以及直接的病毒效应和受感染患者使用皮质类固醇。需要进一步的研究来探索潜在的机制和长期后果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.