{"title":"<i>Candida glabrata</i> Acalculous Cholecystitis in an Immunocompetent Host.","authors":"Abdulazeez Swaiti, Jinye Liu, Hassam Ali, Zarak Khan, Rahul Pamarthy, Khaled Elhusseiny, Danielle Hoo-Fatt","doi":"10.14309/crj.0000000000001802","DOIUrl":null,"url":null,"abstract":"<p><p>Acalculous cholecystitis (AC) is an inflammatory condition of the gallbladder without the presence of gallstones. Although far less common than calculus cholecystitis, AC is associated with a mortality rate 10 times higher than that of calculus cholecystitis. While normally due to bacterial pathogens, opportunistic ones such as the fungi <i>Candida</i> species (spp) can be rare causative agents of AC, typically observed in those with underlying malignancy or immunosuppression. In this study, we present an unusual case of an immunocompetent patient who was afflicted by fluconazole-resistant <i>Candida glabrata</i> AC. Our case highlights the complexity of this diagnosis and the challenges providers may encounter while treating the underlying infection.</p>","PeriodicalId":7394,"journal":{"name":"ACG Case Reports Journal","volume":"12 8","pages":"e01802"},"PeriodicalIF":0.5000,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338181/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACG Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14309/crj.0000000000001802","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Acalculous cholecystitis (AC) is an inflammatory condition of the gallbladder without the presence of gallstones. Although far less common than calculus cholecystitis, AC is associated with a mortality rate 10 times higher than that of calculus cholecystitis. While normally due to bacterial pathogens, opportunistic ones such as the fungi Candida species (spp) can be rare causative agents of AC, typically observed in those with underlying malignancy or immunosuppression. In this study, we present an unusual case of an immunocompetent patient who was afflicted by fluconazole-resistant Candida glabrata AC. Our case highlights the complexity of this diagnosis and the challenges providers may encounter while treating the underlying infection.
期刊介绍：
ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.
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