Prognostic Impact of Non-Impacted Third Molar Extraction on Non-Surgical Periodontal Therapy for Adjacent Second Molars: A Prospective Split-Mouth Study

IF 6.8 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Rui Gao, Hong-Lei Qu, Yi Tian, Li-Juan Sun, Xiao-Tao He, Bei-Min Tian, Yuan Yin, Fa-Ming Chen, Rui-Xin Wu
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引用次数: 0

Abstract

Aims

To compare the outcomes of non-surgical periodontal therapy (NSPT) alone and NSPT plus adjacent non-impacted third molar (N-M3) removal on second molars (M2s).

Materials and Methods

In this prospective split-mouth study, 40 patients with periodontitis who had N-M3s on both sides of the same jaw were enrolled. For each patient, a full-mouth NSPT was performed, with one N-M3 extracted (N-M3−) and the other N-M3 retained (N-M3+). Periodontal clinical parameters, gingival crevicular fluid (GCF) and subgingival plaque samples were measured/collected before (T0), 3 months after (T1) and 6 months after (T2) the treatment.

Results

All M2s showed improved probing depth after treatment. At T1 and T2, M2s in the N-M3− group yielded better outcomes in periodontal clinical parameters than the N-M3+ group, along with a significant decrease in the abundance of periodontal pathogens such as Porphyromonas gingivalis , Prevotella nigrescens and Fusobacterium nucleatum in subgingival plaque. At T2, the M2s in the N-M3− group had significantly lower GCF volume and higher interleukin-10 levels than those in the N-M3+ group.

Conclusion

Over the 6-month observation period, removal of adjacent N-M3s enhanced the outcome of NSPT for second molars, as demonstrated clinically, immunologically and microbiologically.

Trial Registration: Chinese Clinical Trail Registry (identification number: ChiCTR2300070343). https://www.chictr.org.cn/showproj.html?proj=194830 Date of Registration: April 10th, 2023

Abstract Image

非阻生第三磨牙拔除对相邻第二磨牙非手术牙周治疗的预后影响:一项前瞻性裂口研究。
目的比较单纯非手术牙周治疗(NSPT)与NSPT联合邻近无阻生第三磨牙(N-M3)拔除第二磨牙(M2s)的效果。材料和方法在这项前瞻性裂口研究中,纳入了40名患有牙周炎的患者,他们的下颌两侧都有N-M3s。对每位患者进行全口NSPT,取出一个N-M3 (N-M3-),保留另一个N-M3 (N-M3+)。分别于治疗前(T0)、治疗后3个月(T1)和治疗后6个月(T2)测量牙周临床参数、龈沟液(GCF)和龈下菌斑样本。结果治疗后所有M2s探针深度均有所提高。T1和T2时,N-M3-组M2s的牙周临床指标优于N-M3+组,龈下菌斑中牙龈卟啉单胞菌、黑变普氏菌、核梭杆菌等牙周病原菌丰度显著降低。T2时,N-M3-组M2s的GCF体积显著低于N-M3+组,白细胞介素-10水平显著高于N-M3+组。结论在6个月的观察期内,临床、免疫学和微生物学均证实,去除邻近N-M3s可提高第二磨牙NSPT的疗效。中国临床试验注册中心(识别号:ChiCTR2300070343)。https://www.chictr.org.cn/showproj.html?proj=194830报名日期:2023年4月10日。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Clinical Periodontology
Journal of Clinical Periodontology 医学-牙科与口腔外科
CiteScore
13.30
自引率
10.40%
发文量
175
审稿时长
3-8 weeks
期刊介绍: Journal of Clinical Periodontology was founded by the British, Dutch, French, German, Scandinavian, and Swiss Societies of Periodontology. The aim of the Journal of Clinical Periodontology is to provide the platform for exchange of scientific and clinical progress in the field of Periodontology and allied disciplines, and to do so at the highest possible level. The Journal also aims to facilitate the application of new scientific knowledge to the daily practice of the concerned disciplines and addresses both practicing clinicians and academics. The Journal is the official publication of the European Federation of Periodontology but wishes to retain its international scope. The Journal publishes original contributions of high scientific merit in the fields of periodontology and implant dentistry. Its scope encompasses the physiology and pathology of the periodontium, the tissue integration of dental implants, the biology and the modulation of periodontal and alveolar bone healing and regeneration, diagnosis, epidemiology, prevention and therapy of periodontal disease, the clinical aspects of tooth replacement with dental implants, and the comprehensive rehabilitation of the periodontal patient. Review articles by experts on new developments in basic and applied periodontal science and associated dental disciplines, advances in periodontal or implant techniques and procedures, and case reports which illustrate important new information are also welcome.
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