Brain abscess with concurrent infection: tuberculosis and aspergillosis.

IF 2.3 Q2 CLINICAL NEUROLOGY
Shivam Mirg, Jasmine Parihar, Deepti Vibha, Ajay Garg, Gagandeep Singh, Urvashi Singh, M C Sharma, Manjari Tripathi
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引用次数: 0

Abstract

Brain abscess is rarely caused by coinfection with different pathogens. A middle-aged immunocompetent woman developed right-sided focal motor seizures with Todd's palsy. Brain imaging identified a frontal ring-enhancing lesion for which she started antitubercular therapy and corticosteroids. However, on tapering the corticosteroids, she developed a right-sided hemiparesis with increased lesion size. Excision biopsy identified coinfection with Mycobacterium tuberculosis and Aspergillus spp She recovered well with antitubercular and antifungal agents. Coinfections with multiple pathogens pose diagnostic challenges due to overlapping or non-specific clinical and radiological features. This case underscores the importance of tissue diagnosis to enable appropriate therapy.

脑脓肿并发感染:结核和曲霉病。
脑脓肿很少是由不同病原体共同感染引起的。一名免疫功能正常的中年妇女因托德氏麻痹并发右侧局灶性运动癫痫发作。脑成像发现了一个额叶环增强病变,她开始接受抗结核治疗和皮质类固醇治疗。然而,在逐渐减少皮质类固醇治疗后,她出现了右侧偏瘫,病变面积增大。手术切除活检发现合并结核分枝杆菌和曲霉菌感染,使用抗结核和抗真菌药物后恢复良好。由于重叠或非特异性的临床和放射学特征,多种病原体的共感染给诊断带来了挑战。这个病例强调了组织诊断对适当治疗的重要性。
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来源期刊
PRACTICAL NEUROLOGY
PRACTICAL NEUROLOGY Medicine-Neurology (clinical)
CiteScore
3.70
自引率
3.60%
发文量
113
期刊介绍: The essential point of Practical Neurology is that it is practical in the sense of being useful for everyone who sees neurological patients and who wants to keep up to date, and safe, in managing them. In other words this is a journal for jobbing neurologists - which most of us are for at least part of our time - who plough through the tension headaches and funny turns week in and week out. Primary research literature potentially relevant to routine clinical practice is far too much for any neurologist to read, let alone understand, critically appraise and assimilate. Therefore, if research is to influence clinical practice appropriately and quickly it has to be digested and provided to neurologists in an informative and convenient way.
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