Chronic Diabetic Tractional Retinal Detachment and Poor Visual Acuity: Should We Be Performing Surgery on These Patients?

IF 0.8 Q4 OPHTHALMOLOGY
Ryan B Rush, Sloan W Rush
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Abstract

Purpose: To evaluate the benefits of pars plana vitrectomy (PPV) in subjects with poor visual acuity (VA) and a chronic macula-involving tractional retinal detachment (TRD) secondary to proliferative diabetic retinopathy (PDR). Methods: A retrospective, case-controlled chart review was conducted, and patients were divided into (1) a study group that underwent PPV and (2) a control group in which PPV was declined. Both study and control subjects had a baseline VA of hand motions at 3 feet or worse, a PDR-associated macula-involving TRD for more than 6 months, and at least 12 months of follow-up. Results: A total of 175 subjects were analyzed. There were no differences in baseline characteristics between cohorts. The change in VA was improved by 0.78 logMAR (95% CI, 0.64-0.90) in the study group compared with 0.03 logMAR (95% CI, -0.15 to 0.22) in the control group (P < .0001). The rates of achieving 20/200 or better Snellen VA and 20/50 or better Snellen VA were increased in the study group compared with the control group (P < .0001 and P = .007, respectively), and the rates of becoming no light perception, developing neovascular glaucoma, or undergoing enucleation/evisceration during the study period were higher in the control group compared with the study group (P = .02, P < .0001, and P = .03, respectively). Conclusions: Patients with PDR with poor VA and a macula-involving TRD of more than 6 months duration still may have a more meaningful improvement in vision and fewer adverse events when PPV is performed than when PPV is declined in favor of less invasive options.

慢性糖尿病牵引性视网膜脱离和视力低下:我们应该对这些患者进行手术治疗吗?
目的:评价滑膜部玻璃体切除术(PPV)治疗增殖性糖尿病视网膜病变(PDR)继发于视力差(VA)和慢性累及黄斑的牵引性视网膜脱离(TRD)的疗效。方法:采用回顾性病例对照图表法,将患者分为(1)接受PPV治疗的研究组和(2)不接受PPV治疗的对照组。研究和对照组受试者的基线手部运动VA均在3英尺或更差,pdr相关黄斑涉及TRD超过6个月,随访至少12个月。结果:共分析175名受试者。队列之间的基线特征没有差异。研究组的VA变化改善了0.78 logMAR (95% CI, 0.64-0.90),而对照组为0.03 logMAR (95% CI, -0.15至0.22)(P .0001)。与对照组相比,研究组达到20/200或更好的Snellen VA和20/50或更好的Snellen VA的比率增加(分别为P .0001和P = .007),并且在研究期间,对照组无光感、发生新生血管性青光眼或进行去核/内脏切除的比率高于研究组(分别为P = .02、P .0001和P = .03)。结论:对于视力差的PDR患者和持续时间超过6个月的累及黄斑的TRD患者,相比于选择侵入性更小的治疗方案而拒绝PPV治疗,行PPV治疗仍可能有更有意义的视力改善和更少的不良事件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.20
自引率
16.70%
发文量
0
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