Implementation of hazard analysis and critical control points (HACCP) for microbial safety of enteral feeding solutions at Imam Khomeini Hospital, Urmia, Iran.

IF 1.7 Q4 MICROBIOLOGY

Iranian Journal of Microbiology Pub Date : 2025-08-01 DOI:10.18502/ijm.v17i4.19251

Mohammad Yousefi, Kave Koorehpaz, Morteza Bagheri, Yaghob Sharifi, Amir Rahimirad, Yousef Roosta

{"title":"Implementation of hazard analysis and critical control points (HACCP) for microbial safety of enteral feeding solutions at Imam Khomeini Hospital, Urmia, Iran.","authors":"Mohammad Yousefi, Kave Koorehpaz, Morteza Bagheri, Yaghob Sharifi, Amir Rahimirad, Yousef Roosta","doi":"10.18502/ijm.v17i4.19251","DOIUrl":null,"url":null,"abstract":"Background and objectives: Enteral feeding solutions (gavage) play a vital role in supporting ICU patients who cannot eat by mouth. However, their preparation is vulnerable to microbial contamination, posing serious health risks. This study aimed to assess and improve the microbial safety of enteral feeding solutions prepared at Imam Khomeini Hospital in Urmia, Iran.Materials and methods: A three-phase intervention was conducted involving microbial and PCR analyses, source identification, and corrective measures. Initial testing revealed high contamination levels: coliform bacteria (>5×103 CFU/mL), fungi (>3×103 CFU/mL), and total mesophilic bacteria (>104 CFU/mL). PCR analysis confirmed the absence of Escherichia coli and Klebsiella spp. Corrective actions-such as installing UV lighting, implementing enhanced cleaning protocols, and replacing the mixing device-were introduced.Results: Post-intervention analyses showed complete elimination of detectable microbial contamination in the gavage solutions.Conclusion: This study demonstrates that implementing a HACCP-based approach can effectively eliminate microbial contamination in enteral feeding solutions. The findings support the development of national guidelines and highlight the importance of standardized safety practices to improve patient care in hospital settings.","PeriodicalId":14633,"journal":{"name":"Iranian Journal of Microbiology","volume":"17 4","pages":"606-612"},"PeriodicalIF":1.7000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331463/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18502/ijm.v17i4.19251","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background and objectives: Enteral feeding solutions (gavage) play a vital role in supporting ICU patients who cannot eat by mouth. However, their preparation is vulnerable to microbial contamination, posing serious health risks. This study aimed to assess and improve the microbial safety of enteral feeding solutions prepared at Imam Khomeini Hospital in Urmia, Iran.

Materials and methods: A three-phase intervention was conducted involving microbial and PCR analyses, source identification, and corrective measures. Initial testing revealed high contamination levels: coliform bacteria (>5×10³ CFU/mL), fungi (>3×10³ CFU/mL), and total mesophilic bacteria (>10⁴ CFU/mL). PCR analysis confirmed the absence of Escherichia coli and Klebsiella spp. Corrective actions-such as installing UV lighting, implementing enhanced cleaning protocols, and replacing the mixing device-were introduced.

Results: Post-intervention analyses showed complete elimination of detectable microbial contamination in the gavage solutions.

Conclusion: This study demonstrates that implementing a HACCP-based approach can effectively eliminate microbial contamination in enteral feeding solutions. The findings support the development of national guidelines and highlight the importance of standardized safety practices to improve patient care in hospital settings.

Abstract Image

查看原文本刊更多论文

在伊朗乌尔米亚伊玛目霍梅尼医院实施肠道喂养液微生物安全危害分析和关键控制点（HACCP）。

背景和目的：肠内喂养溶液（灌胃）在支持不能通过口腔进食的ICU患者中起着至关重要的作用。然而，它们的制备容易受到微生物污染，构成严重的健康风险。本研究旨在评估和提高伊朗乌尔米亚伊玛目霍梅尼医院制备的肠内喂养液的微生物安全性。材料和方法：进行了三个阶段的干预，包括微生物和PCR分析，来源鉴定和纠正措施。初步检测显示高污染水平：大肠菌群（>5×103 CFU/mL），真菌（>3×103 CFU/mL）和总中温细菌（>104 CFU/mL）。PCR分析证实没有大肠杆菌和克雷伯氏菌，并采取了纠正措施，如安装紫外线照明，实施强化清洁方案，更换混合装置。结果：干预后分析显示灌胃液中可检测的微生物污染完全消除。结论：本研究表明，实施基于haccp的方法可以有效消除肠内喂养液中的微生物污染。研究结果支持国家指南的制定，并强调了标准化安全实践对改善医院环境中患者护理的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.