Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
International Medical Case Reports Journal Pub Date : 2025-08-05 eCollection Date: 2025-01-01 DOI:10.2147/IMCRJ.S529728
Aisyah Shofiatun Nisa, Hadi Susiarno, Gatot Nyarumenteng Adipurnawan Winarno, Putri Nadhira Adinda Adriansyah
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Abstract

Introduction: Hydrops fetalis is a condition characterized by excessive fluid accumulation within the fetal extravascular compartments and body cavities. It is classified into two categories: immune hydrops fetalis (IHF) and non-immune hydrops fetalis (NIHF). The primary cause of NIHF is fetal cardiovascular abnormalities, often stemming from congenital heart disease. One of the significant contributors to congenital heart defects is prenatal alcohol exposure (PAE).

Case illustration: A woman in her early 30s presented to the emergency department with the chief complaint of not feeling fetal movements for one day prior to admission. This was her fourth pregnancy, with no history of miscarriage or abortion. The patient reported a history of regular smoking (two packs per day) and frequent alcohol consumption. Her vital signs were unremarkable upon admission. The baby was delivered weighing 1755 grams and measuring 44 cm, with grade 2 maceration and no signs of life. Physical findings, including fluid accumulation in the chest and body, led to a pediatric diagnosis of hydrops fetalis.

Conclusion: The risk factor for hydrops fetalis in this case is likely associated with prenatal alcohol exposure, which may have disrupted fetal teratogenesis. Comprehensive prenatal examinations are essential for monitoring fetal health, identifying complications and congenital abnormalities, and assessing risk factors.

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慢性饮酒孕妇的非免疫性水肿胎儿1例报告
胎儿积水是一种以胎儿血管外腔和体腔内液体积聚过多为特征的疾病。它分为两类:免疫性积水胎儿(IHF)和非免疫性积水胎儿(NIHF)。NIHF的主要原因是胎儿心血管异常,通常源于先天性心脏病。造成先天性心脏缺陷的一个重要因素是产前酒精暴露(PAE)。病例说明:一名30岁出头的妇女以入院前一天感觉不到胎动为主诉来到急诊科。这是她第四次怀孕,没有流产或流产史。患者报告有经常吸烟(每天两包)和经常饮酒的历史。入院时她的生命体征并不明显。婴儿出生时体重1755克,身高44厘米,浸渍程度为2级,没有生命迹象。身体检查结果,包括胸部和身体的液体积聚,导致儿科诊断为胎儿水肿。结论:本例胎儿水肿的危险因素可能与产前酒精暴露有关,酒精暴露可能破坏胎儿畸形。全面的产前检查对于监测胎儿健康、确定并发症和先天性异常以及评估危险因素至关重要。
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来源期刊
International Medical Case Reports Journal
International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
135
审稿时长
16 weeks
期刊介绍: International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
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