{"title":"Non-Immune Hydrops Fetalis in a Pregnant Woman with Chronic Alcohol Use: A Case Report.","authors":"Aisyah Shofiatun Nisa, Hadi Susiarno, Gatot Nyarumenteng Adipurnawan Winarno, Putri Nadhira Adinda Adriansyah","doi":"10.2147/IMCRJ.S529728","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Hydrops fetalis is a condition characterized by excessive fluid accumulation within the fetal extravascular compartments and body cavities. It is classified into two categories: immune hydrops fetalis (IHF) and non-immune hydrops fetalis (NIHF). The primary cause of NIHF is fetal cardiovascular abnormalities, often stemming from congenital heart disease. One of the significant contributors to congenital heart defects is prenatal alcohol exposure (PAE).</p><p><strong>Case illustration: </strong>A woman in her early 30s presented to the emergency department with the chief complaint of not feeling fetal movements for one day prior to admission. This was her fourth pregnancy, with no history of miscarriage or abortion. The patient reported a history of regular smoking (two packs per day) and frequent alcohol consumption. Her vital signs were unremarkable upon admission. The baby was delivered weighing 1755 grams and measuring 44 cm, with grade 2 maceration and no signs of life. Physical findings, including fluid accumulation in the chest and body, led to a pediatric diagnosis of hydrops fetalis.</p><p><strong>Conclusion: </strong>The risk factor for hydrops fetalis in this case is likely associated with prenatal alcohol exposure, which may have disrupted fetal teratogenesis. Comprehensive prenatal examinations are essential for monitoring fetal health, identifying complications and congenital abnormalities, and assessing risk factors.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"969-975"},"PeriodicalIF":0.7000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12335259/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Medical Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/IMCRJ.S529728","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Hydrops fetalis is a condition characterized by excessive fluid accumulation within the fetal extravascular compartments and body cavities. It is classified into two categories: immune hydrops fetalis (IHF) and non-immune hydrops fetalis (NIHF). The primary cause of NIHF is fetal cardiovascular abnormalities, often stemming from congenital heart disease. One of the significant contributors to congenital heart defects is prenatal alcohol exposure (PAE).
Case illustration: A woman in her early 30s presented to the emergency department with the chief complaint of not feeling fetal movements for one day prior to admission. This was her fourth pregnancy, with no history of miscarriage or abortion. The patient reported a history of regular smoking (two packs per day) and frequent alcohol consumption. Her vital signs were unremarkable upon admission. The baby was delivered weighing 1755 grams and measuring 44 cm, with grade 2 maceration and no signs of life. Physical findings, including fluid accumulation in the chest and body, led to a pediatric diagnosis of hydrops fetalis.
Conclusion: The risk factor for hydrops fetalis in this case is likely associated with prenatal alcohol exposure, which may have disrupted fetal teratogenesis. Comprehensive prenatal examinations are essential for monitoring fetal health, identifying complications and congenital abnormalities, and assessing risk factors.
期刊介绍:
International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.