Comparison of Oral Health Status of Pediatric Patients with Gastroesophageal Reflux and Bile Reflux Disease.

IF 2.6 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Caries Research Pub Date : 2025-08-08 DOI:10.1159/000547887

Makbule Buse Dundar Sari, Eren Sari, Melike Arslan, Merve Aksoy, Cenkhan Bal, Necati Balamtekin

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引用次数: 0

Abstract

Introduction: Gastroesophageal reflux disease (GERD) and bile reflux disease (BRD) are two distinct conditions that may affect oral health through different mechanisms. This study investigated whether these reflux types lead to differing oral and dental outcomes in pediatric patients, aiming to inform clinical practice and promote interdisciplinary care.

Methods: Patients diagnosed with BRD or GERD between 2017 and 2020 were included. Clinical oral examinations, salivary analyses, and questionnaires on potential etiological factors for erosive tooth wear (ETW) were conducted. Oral health was assessed using the Basic Erosive Wear Examination (BEWE), dental caries experience (DMFT), Silness and Löe plaque index (PI), and gingival index (GI). Salivary pH and flow rates were recorded.

Results: Sixty-six patients (33 with BRD, 33 with GERD; 75.8% female; mean age: 14.9 ± 3.1) were included. BEWE scores were significantly higher in GERD patients (median: 6 vs. 4) (p < 0.001), though both groups were classified as low risk for ETW. GERD patients had higher PI (p = 0.018) and GI scores (p < 0.001), while DMFT scores were similar (p = 0.639). BRD patients exhibited significantly higher median values for unstimulated and stimulated salivary pH (7 vs. 6 and 8 vs. 7, respectively) and flow rates (0.6 vs. 0.36 mL/min and 1.7 vs. 1.22 mL/min, respectively) (all p < 0.001), although stimulated flow in GERD patients remained within normal limits (≥1 mL/min).

Conclusion: GERD was associated with poorer oral health, particularly ETW and gingival status. Early, multidisciplinary intervention may help prevent erosion and promote remineralization.

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小儿胃食管反流与胆汁反流病患者口腔健康状况的比较

胃食管反流病（GERD）和胆汁反流病（BRD）是两种不同的疾病，可能通过不同的机制影响口腔健康。本研究调查了这些反流类型是否会导致儿科患者口腔和牙科预后的不同，旨在为临床实践提供信息并促进跨学科护理。方法：纳入2017 - 2020年间诊断为BRD或GERD的患者。临床口腔检查、唾液分析和调查糜烂性牙齿磨损（ETW）的潜在病因。使用基本侵蚀磨损检查（BEWE）、龋齿经历（DMFT）、Silness和Löe菌斑指数（PI）以及牙龈指数（GI）评估口腔健康。记录唾液pH值和流速。结果：66例患者(BRD 33例，GERD 33例；75.8%的女性;平均年龄：14.9±3.1)。GERD患者的BEWE评分明显更高（中位数：6比4）（p < 0.001），尽管两组均被归为ETW低风险。GERD患者PI （p = 0.018）和GI评分较高（p < 0.001），而DMFT评分相近（p = 0.639）。BRD患者未刺激和刺激的唾液pH值（分别为7 vs. 6和8 vs. 7）和流速（分别为0.6 vs. 0.36 ml/min和1.7 vs. 1.22 ml/min）的中位数值显着更高（均p < 0.001），尽管GERD患者的刺激流量仍在正常范围内（≥1ml /min）。结论：胃食管反流与较差的口腔健康状况有关，尤其是ETW和牙龈状况。早期多学科干预可能有助于防止侵蚀和促进再矿化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Caries Research 医学-牙科与口腔外科

CiteScore

6.30

自引率

7.10%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Caries Research'' publishes epidemiological, clinical and laboratory studies in dental caries, erosion and related dental diseases. Some studies build on the considerable advances already made in caries prevention, e.g. through fluoride application. Some aim to improve understanding of the increasingly important problem of dental erosion and the associated tooth wear process. Others monitor the changing pattern of caries in different populations, explore improved methods of diagnosis or evaluate methods of prevention or treatment. The broad coverage of current research has given the journal an international reputation as an indispensable source for both basic scientists and clinicians engaged in understanding, investigating and preventing dental disease.