Tailored mechanical properties of silicon nitride–hydroxyapatite composite scaffolds for biomedical applications

IF 2.3 4区材料科学 Q2 MATERIALS SCIENCE, CERAMICS

International Journal of Applied Ceramic Technology Pub Date : 2025-06-17 DOI:10.1111/ijac.70007

Guido de La Torre Olvera, Miroslav Hnatko, Magdaléna Precnerová, Ivo Dlouhý, Monika Tatarková

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Abstract

Silicon nitride (Si₃N₄)–hydroxyapatite (HA) composite scaffolds for bone replacement were developed via pressure infiltration of HA into a porous Si₃N₄ matrix. The effect of replication processing parameters (SiO₂ content, number of infiltrations, and calcination temperature) on the structure and mechanical properties of the porous Si₃N₄ matrix was investigated and compared to human trabecular bone. All fabricated Si₃N₄ matrices exhibited interconnected porosity comparable to trabecular bone. A matrix processed with double infiltration with 15 wt.% SiO₂ suspension, followed by calcination at 1100°C, demonstrated the highest compressive strength. Subsequent pressure infiltration with HA significantly enhanced both the compressive (∼ twofold) and tensile strength (> quadruple) of this matrix, yielding a composite scaffold with a compressive strength similar to that of human trabecular bone, while maintaining comparable microporosity.

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生物医学应用氮化硅-羟基磷灰石复合支架的定制力学性能

将氮化硅(Si3N4) -羟基磷灰石（HA）复合材料通过压力渗透到多孔的Si3N4基质中制备骨置换支架。研究了复制工艺参数（SiO2含量、浸润次数和煅烧温度）对多孔Si3N4基质结构和力学性能的影响，并与人小梁骨进行了比较。所有制备的氮化硅基质都表现出与小梁骨相似的互连孔隙度。以15wt .% SiO2悬浮液进行二次浸渍处理，然后在1100℃下煅烧，其抗压强度最高。随后的HA压渗显著提高了抗压强度（~ 2倍）和抗拉强度(>；这种基质的四倍，产生的复合支架具有类似于人类小梁骨的抗压强度，同时保持相当的微孔隙率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Applied Ceramic Technology 工程技术-材料科学：硅酸盐

CiteScore

3.90

自引率

9.50%

发文量

280

审稿时长

4.5 months

期刊介绍： The International Journal of Applied Ceramic Technology publishes cutting edge applied research and development work focused on commercialization of engineered ceramics, products and processes. The publication also explores the barriers to commercialization, design and testing, environmental health issues, international standardization activities, databases, and cost models. Designed to get high quality information to end-users quickly, the peer process is led by an editorial board of experts from industry, government, and universities. Each issue focuses on a high-interest, high-impact topic plus includes a range of papers detailing applications of ceramics. Papers on all aspects of applied ceramics are welcome including those in the following areas: Nanotechnology applications; Ceramic Armor; Ceramic and Technology for Energy Applications (e.g., Fuel Cells, Batteries, Solar, Thermoelectric, and HT Superconductors); Ceramic Matrix Composites; Functional Materials; Thermal and Environmental Barrier Coatings; Bioceramic Applications; Green Manufacturing; Ceramic Processing; Glass Technology; Fiber optics; Ceramics in Environmental Applications; Ceramics in Electronic, Photonic and Magnetic Applications;