Beam Shaping Assembly of the VITA Accelerator-Based Neutron Source

IF 0.4 Q4 PHYSICS, PARTICLES & FIELDS
T. V. Shein, E. A. Berendeev, V. S. Degtyarev, A. M. Koshkarev, A. S. Kuznetsov, S. S. Savinov, S. Yu. Taskaev
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引用次数: 0

Abstract

The VITA accelerator-based neutron source has been proposed and developed at the Budker Institute of Nuclear Physics (Novosibirsk, Russia) for boron neutron capture therapy (BNCT), which includes a vacuum-insulated tandem accelerator for proton beam production, a lithium target for neutron generation through the 7Li(p, n)7Be reaction, and a neutron beam shaping assembly (BSA) with MgF2 moderator for therapeutic beam generation. This paper presents a comparison of the results of numerical simulations of boron dose and γ-ray dose spatial distributions in a water phantom for three different neutron beam shaping assemblies. The investigations are carried out at the VITA accelerator-based neutron source in the Budker Institute of Nuclear Physics, Siberian branch, Russian Academy of Sciences, using a small neutron detector to measure these components of ionizing radiation. An agreement between the measured and simulated results is obtained. For the VITA accelerator neutron source that was manufactured and is being supplied to the Blokhin National Medical Research Center of Oncology in Moscow with the purpose of conducting clinical trials of the BNCT technique in Russia and the subsequent treatment of patients, the BSA is optimized by numerical simulation with consideration for the equipment, the presence of structural materials, and the wall separating the installation room from the irradiation room. The description of materials that make it possible to form a neutron beam that meets the requirements of the BNCT and the design of manufactured BSA is presented.

Abstract Image

Abstract Image

基于VITA加速器的中子源束整形组件
Budker核物理研究所(Novosibirsk, Russia)提出并开发了基于VITA加速器的中子源,用于硼中子捕获治疗(BNCT),其中包括用于产生质子束的真空绝缘串列加速器,通过7Li(p, n)7Be反应产生中子的锂靶,以及用于产生治疗束的含MgF2减速剂的中子束成形组件(BSA)。本文比较了三种不同中子束整形装置在水影中硼剂量和γ射线剂量空间分布的数值模拟结果。这项研究是在俄罗斯科学院西伯利亚分院Budker核物理研究所的VITA加速器中子源上进行的,使用一个小型中子探测器来测量这些电离辐射的成分。仿真结果与实测结果吻合。为了在俄罗斯进行BNCT技术的临床试验和随后的患者治疗,VITA加速器中子源已制造并供应给莫斯科的Blokhin国家肿瘤医学研究中心,BSA通过数值模拟进行了优化,考虑了设备、结构材料的存在以及将安装室与照射室分开的墙壁。介绍了能够形成满足BNCT要求的中子束的材料和制造的BSA的设计。
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来源期刊
Physics of Particles and Nuclei Letters
Physics of Particles and Nuclei Letters PHYSICS, PARTICLES & FIELDS-
CiteScore
0.80
自引率
20.00%
发文量
108
期刊介绍: The journal Physics of Particles and Nuclei Letters, brief name Particles and Nuclei Letters, publishes the articles with results of the original theoretical, experimental, scientific-technical, methodological and applied research. Subject matter of articles covers: theoretical physics, elementary particle physics, relativistic nuclear physics, nuclear physics and related problems in other branches of physics, neutron physics, condensed matter physics, physics and engineering at low temperatures, physics and engineering of accelerators, physical experimental instruments and methods, physical computation experiments, applied research in these branches of physics and radiology, ecology and nuclear medicine.
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