Phoma Fungi: Ecological Diversity, Specialized Metabolites, and Biological Activities.

IF 2.5 3区 化学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
Xun-Feng Chen, Yong-Sha Guo, Xu-Hong Wei, Qiu-Yan Song
{"title":"Phoma Fungi: Ecological Diversity, Specialized Metabolites, and Biological Activities.","authors":"Xun-Feng Chen, Yong-Sha Guo, Xu-Hong Wei, Qiu-Yan Song","doi":"10.1002/cbdv.202500856","DOIUrl":null,"url":null,"abstract":"<p><p>Phoma species are globally widespread, thriving in a diverse array of ecological niches. Between 2020 and 2025, there were newly found Phoma species as endophytes (six species), saprophytes (three species), and pathogens (six species). Moreover, the genus Phoma is a treasure trove of bioactive specialized metabolites, holding significant potential for human applications. This article offers a comprehensive summary of 96 specialized metabolites identified within the genus Phoma, comprising 44 polyketides, 18 macrolides, 24 alkaloids, and 10 sterols. It provides detailed insights into their associated biological activities, including cytotoxicity, antifungal properties, and anti-angiogenic effects. This compilation is intended to lay a solid theoretical foundation for the exploitation and utilization of Phoma fungal resources.</p>","PeriodicalId":9878,"journal":{"name":"Chemistry & Biodiversity","volume":" ","pages":"e00856"},"PeriodicalIF":2.5000,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry & Biodiversity","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/cbdv.202500856","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Phoma species are globally widespread, thriving in a diverse array of ecological niches. Between 2020 and 2025, there were newly found Phoma species as endophytes (six species), saprophytes (three species), and pathogens (six species). Moreover, the genus Phoma is a treasure trove of bioactive specialized metabolites, holding significant potential for human applications. This article offers a comprehensive summary of 96 specialized metabolites identified within the genus Phoma, comprising 44 polyketides, 18 macrolides, 24 alkaloids, and 10 sterols. It provides detailed insights into their associated biological activities, including cytotoxicity, antifungal properties, and anti-angiogenic effects. This compilation is intended to lay a solid theoretical foundation for the exploitation and utilization of Phoma fungal resources.

真菌:生态多样性、特殊代谢物和生物活性。
Phoma物种在全球范围内广泛分布,在各种生态位中蓬勃发展。2020 - 2025年间,新发现的蕨类植物有内生植物(6种)、腐生植物(3种)和致病菌(6种)。此外,Phoma属是生物活性特化代谢物的宝库,具有重大的人类应用潜力。这篇文章提供了96种特殊代谢物的综合总结,其中包括44种聚酮,18种大环内酯,24种生物碱和10种甾醇。它提供了详细的见解,其相关的生物活性,包括细胞毒性,抗真菌特性和抗血管生成的作用。旨在为真菌资源的开发利用奠定坚实的理论基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Chemistry & Biodiversity
Chemistry & Biodiversity 环境科学-化学综合
CiteScore
3.40
自引率
10.30%
发文量
475
审稿时长
2.6 months
期刊介绍: Chemistry & Biodiversity serves as a high-quality publishing forum covering a wide range of biorelevant topics for a truly international audience. This journal publishes both field-specific and interdisciplinary contributions on all aspects of biologically relevant chemistry research in the form of full-length original papers, short communications, invited reviews, and commentaries. It covers all research fields straddling the border between the chemical and biological sciences, with the ultimate goal of broadening our understanding of how nature works at a molecular level. Since 2017, Chemistry & Biodiversity is published in an online-only format.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信