Roles of bio-based microplastics in modulating the toxic effects of the herbicide metolachlor on the South American native species Palaemon argentinus: Single and co-exposure effects

IF 4.3 2区 环境科学与生态学 Q1 MARINE & FRESHWATER BIOLOGY
Lidwina Bertrand , Naomi Carolina Yacelga Villavicencio , Guido Noé Rimondino , María Florencia Gonzalez , María Valeria Amé
{"title":"Roles of bio-based microplastics in modulating the toxic effects of the herbicide metolachlor on the South American native species Palaemon argentinus: Single and co-exposure effects","authors":"Lidwina Bertrand ,&nbsp;Naomi Carolina Yacelga Villavicencio ,&nbsp;Guido Noé Rimondino ,&nbsp;María Florencia Gonzalez ,&nbsp;María Valeria Amé","doi":"10.1016/j.aquatox.2025.107532","DOIUrl":null,"url":null,"abstract":"<div><div>Microplastics (MPs), including those from bio-based plastics (BBPs), are increasingly detected in aquatic ecosystems, raising concerns about their role in modifying pollutant toxicity. This study investigated environmentally relevant concentrations of polylactic acid microplastics (PLA-MPs) on the South American native shrimp <em>Palaemon argentinus</em>, evaluating single and co-exposure scenarios with metolachlor (MET) over a 7-day bioassay. Characterization of PLA-MPs revealed a fragment shape with typical PLA spectroscopic pattern and an elemental composition of &gt;80 % C and ∼15 % O. Both PLA-MPs and MET accumulated in the shrimp, causing oxidative stress, neurotoxicity, and tissue damage. Significant inhibition of acetylcholinesterase in shrimp exposed to PLA-MPs suggests impaired locomotion and behavior, which may affect population dynamics and ecosystem function. The MET adsorption on PLA-MPs was confirmed under tested conditions. The co-exposure increased MET prevalence in the cephalothorax, indicating the role of BBP particles as pesticide transporters in aquatic ecosystems. In addition, calculated bioaccumulation factors suggested a minimal trophic transfer of MET under the tested conditions. The integrated biomarker response revealed co-exposure stress levels intermediate between MET exposure and PLA-MPs treatment, suggesting partial antagonistic interactions. Reduced cytoplasmic MET bioavailability via PLA-MP adsorption was hypothesized as the underlying mechanism. These results indicate complex MP-chemical interactions, with possible antagonistic effects at the biochemical and tissue levels, and highlight the need for further research on the ecotoxicity of BBPs. Greater efforts are needed to elucidate the role of plastic additives in toxicity and the role of MPs in the bioaccumulation processes of pesticides. This would be useful to assess the environmental impact of BBPs and determine their viability as a sustainable alternative to conventional plastics.</div></div>","PeriodicalId":248,"journal":{"name":"Aquatic Toxicology","volume":"287 ","pages":"Article 107532"},"PeriodicalIF":4.3000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aquatic Toxicology","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0166445X25002966","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MARINE & FRESHWATER BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Microplastics (MPs), including those from bio-based plastics (BBPs), are increasingly detected in aquatic ecosystems, raising concerns about their role in modifying pollutant toxicity. This study investigated environmentally relevant concentrations of polylactic acid microplastics (PLA-MPs) on the South American native shrimp Palaemon argentinus, evaluating single and co-exposure scenarios with metolachlor (MET) over a 7-day bioassay. Characterization of PLA-MPs revealed a fragment shape with typical PLA spectroscopic pattern and an elemental composition of >80 % C and ∼15 % O. Both PLA-MPs and MET accumulated in the shrimp, causing oxidative stress, neurotoxicity, and tissue damage. Significant inhibition of acetylcholinesterase in shrimp exposed to PLA-MPs suggests impaired locomotion and behavior, which may affect population dynamics and ecosystem function. The MET adsorption on PLA-MPs was confirmed under tested conditions. The co-exposure increased MET prevalence in the cephalothorax, indicating the role of BBP particles as pesticide transporters in aquatic ecosystems. In addition, calculated bioaccumulation factors suggested a minimal trophic transfer of MET under the tested conditions. The integrated biomarker response revealed co-exposure stress levels intermediate between MET exposure and PLA-MPs treatment, suggesting partial antagonistic interactions. Reduced cytoplasmic MET bioavailability via PLA-MP adsorption was hypothesized as the underlying mechanism. These results indicate complex MP-chemical interactions, with possible antagonistic effects at the biochemical and tissue levels, and highlight the need for further research on the ecotoxicity of BBPs. Greater efforts are needed to elucidate the role of plastic additives in toxicity and the role of MPs in the bioaccumulation processes of pesticides. This would be useful to assess the environmental impact of BBPs and determine their viability as a sustainable alternative to conventional plastics.

Abstract Image

生物基微塑料在调节除草剂异甲草胺对南美本土物种阿根廷古鲑的毒性作用中的作用:单一和共同暴露效应
微塑料(MPs),包括来自生物基塑料(BBPs)的微塑料,越来越多地在水生生态系统中被检测到,这引起了人们对它们在改变污染物毒性方面的作用的关注。本研究调查了南美本地对虾(Palaemon argentinus)体内聚乳酸微塑料(PLA-MPs)的环境相关浓度,在为期7天的生物测定中评估了与异丙甲草胺(MET)单独和共同暴露的情况。PLA- mps的表征显示出具有典型PLA光谱模式的片段形状,元素组成为>; 80% C和~ 15% o。PLA- mps和MET都在虾体内积累,导致氧化应激、神经毒性和组织损伤。暴露于PLA-MPs的对虾的乙酰胆碱酯酶显著抑制表明运动和行为受损,可能影响种群动态和生态系统功能。在测试条件下证实了PLA-MPs对MET的吸附。共同暴露增加了头胸中MET的患病率,表明BBP颗粒在水生生态系统中作为农药转运体的作用。此外,计算的生物积累因子表明,在试验条件下,MET的营养转移最小。综合生物标志物反应显示,共暴露应激水平介于MET暴露和PLA-MPs治疗之间,表明存在部分拮抗作用。通过PLA-MP吸附降低细胞质MET生物利用度被假设为潜在的机制。这些结果表明了复杂的mp -化学相互作用,在生化和组织水平上可能具有拮抗作用,并强调了对BBPs生态毒性进一步研究的必要性。塑料添加剂在毒性中的作用以及MPs在农药生物积累过程中的作用有待进一步研究。这将有助于评估bbp对环境的影响,并确定其作为传统塑料的可持续替代品的可行性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Aquatic Toxicology
Aquatic Toxicology 环境科学-毒理学
CiteScore
7.10
自引率
4.40%
发文量
250
审稿时长
56 days
期刊介绍: Aquatic Toxicology publishes significant contributions that increase the understanding of the impact of harmful substances (including natural and synthetic chemicals) on aquatic organisms and ecosystems. Aquatic Toxicology considers both laboratory and field studies with a focus on marine/ freshwater environments. We strive to attract high quality original scientific papers, critical reviews and expert opinion papers in the following areas: Effects of harmful substances on molecular, cellular, sub-organismal, organismal, population, community, and ecosystem level; Toxic Mechanisms; Genetic disturbances, transgenerational effects, behavioral and adaptive responses; Impacts of harmful substances on structure, function of and services provided by aquatic ecosystems; Mixture toxicity assessment; Statistical approaches to predict exposure to and hazards of contaminants The journal also considers manuscripts in other areas, such as the development of innovative concepts, approaches, and methodologies, which promote the wider application of toxicological datasets to the protection of aquatic environments and inform ecological risk assessments and decision making by relevant authorities.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信