The Zebrafish Neurobehavioral Catalog-Volume 2 (New Addition).

Abstract

The zebrafish is no longer a shy "beginner" but a key model species in neuroscience and drug discovery research. Understanding zebrafish behaviors is important for developing valid models of brain disorders and probing their genetic and environmental causes. The rapid development of zebrafish-based tests and screens also necessitates formal and consistent terminology for the observed phenotypes and behavioral phenomena. To address these needs, in 2013 we compiled a comprehensive 'consensus' glossary of nearly 190 zebrafish behaviors-the Zebrafish Behavior Catalog (ZBC-1) for both larval and adult fish. However, as novel zebrafish behaviors continue to be recognized, an expansion and revision of ZBC were deemed timely. Here, we present the next additional volume of the catalog (ZBC-2), which describes over 120 novel zebrafish behavioral terms and, like the original project, represents a result of a global teamwork of multiple collaborating zebrafish laboratories. Illustrating the value of community efforts to improve data replicability and reliability, this catalog is expected to help interpret research findings, foster cross-domain and cross-species modeling, and encourage new laboratories to study zebrafish behavioral phenotypes.