Megan E Frayer, Nemo V Robles, María José Rodríguez-Barrera, Jenn M Coughlan, Molly Schumer
{"title":"The molecular evolutionary basis of species formation revisited.","authors":"Megan E Frayer, Nemo V Robles, María José Rodríguez-Barrera, Jenn M Coughlan, Molly Schumer","doi":"10.1016/j.tig.2025.07.003","DOIUrl":null,"url":null,"abstract":"<p><p>How do new species arise? This is among the most fundamental questions in evolutionary biology. The first genetic model for how reproductive barriers lead to the origin of new species was proposed nearly 90 years ago. However, empirical evidence for the genetic mechanisms that cause reproductive barriers took many decades to accumulate. In 2010, Presgraves presented a comprehensive review of the literature on known 'speciation genes' and the possible evolutionary mechanisms through which they arose. Fifteen years later, with an explosion of studies that include both non-model and model organisms, the number of known hybrid incompatibility genes has increased approximately sevenfold. Here, we synthesize previous and new empirical examples to investigate the genetic mechanisms through which intrinsic incompatibilities in hybrids arise and highlight current gaps in our understanding.</p>","PeriodicalId":54413,"journal":{"name":"Trends in Genetics","volume":" ","pages":""},"PeriodicalIF":16.3000,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Genetics","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.tig.2025.07.003","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"GENETICS & HEREDITY","Score":null,"Total":0}
引用次数: 0
Abstract
How do new species arise? This is among the most fundamental questions in evolutionary biology. The first genetic model for how reproductive barriers lead to the origin of new species was proposed nearly 90 years ago. However, empirical evidence for the genetic mechanisms that cause reproductive barriers took many decades to accumulate. In 2010, Presgraves presented a comprehensive review of the literature on known 'speciation genes' and the possible evolutionary mechanisms through which they arose. Fifteen years later, with an explosion of studies that include both non-model and model organisms, the number of known hybrid incompatibility genes has increased approximately sevenfold. Here, we synthesize previous and new empirical examples to investigate the genetic mechanisms through which intrinsic incompatibilities in hybrids arise and highlight current gaps in our understanding.
期刊介绍：
Launched in 1985, Trends in Genetics swiftly established itself as a "must-read" for geneticists, offering concise, accessible articles covering a spectrum of topics from developmental biology to evolution. This reputation endures, making TiG a cherished resource in the genetic research community. While evolving with the field, the journal now embraces new areas like genomics, epigenetics, and computational genetics, alongside its continued coverage of traditional subjects such as transcriptional regulation, population genetics, and chromosome biology.
Despite expanding its scope, the core objective of TiG remains steadfast: to furnish researchers and students with high-quality, innovative reviews, commentaries, and discussions, fostering an appreciation for advances in genetic research. Each issue of TiG presents lively and up-to-date Reviews and Opinions, alongside shorter articles like Science & Society and Spotlight pieces. Invited from leading researchers, Reviews objectively chronicle recent developments, Opinions provide a forum for debate and hypothesis, and shorter articles explore the intersection of genetics with science and policy, as well as emerging ideas in the field. All articles undergo rigorous peer-review.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
