{"title":"Timing matters: Genetic regulation of neuronal maturation in the primate brain.","authors":"Kent Imaizumi, Sergiu P Paşca","doi":"10.1016/j.neuron.2025.07.013","DOIUrl":null,"url":null,"abstract":"<p><p>The molecular mechanisms that govern the extended neuronal maturation in the primate brain remain incompletely understood. In this issue of Neuron, Gao et al.<sup>1</sup> measure gene activity, chromatin state, and electrical properties of individual neurons in the macaque to reveal some of the genetic regulators of neuronal maturation in the cerebral cortex.</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 15","pages":"2375-2377"},"PeriodicalIF":15.0000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.07.013","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The molecular mechanisms that govern the extended neuronal maturation in the primate brain remain incompletely understood. In this issue of Neuron, Gao et al.1 measure gene activity, chromatin state, and electrical properties of individual neurons in the macaque to reveal some of the genetic regulators of neuronal maturation in the cerebral cortex.
期刊介绍:
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.