Context is everything: The role of polo-like kinase I during C. elegans oocyte meiosis.

IF 6.4 1区生物学 Q1 CELL BIOLOGY

Journal of Cell Biology Pub Date : 2025-08-08 DOI:10.1083/jcb.202506208

Needhi Bhalla

引用次数: 0

Abstract

Meiotic chromosome segregation in oocytes often relies on meiosis-specific modifications of mitotic molecular mechanisms to respond to the unique challenges of this asymmetric division. In this issue, Narula and Wignall (https://doi.org/10.1083/jcb.202503080) demonstrate how the conserved polo-like kinase in Caenorhabditiselegans, PLK-1, has been repurposed in unexpected ways to ensure accurate meiotic chromosome segregation during oogenesis.

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环境决定一切：polo样激酶I在秀丽隐杆线虫卵母细胞减数分裂中的作用。

在这一期中，Narula和Wignall （https://doi.org/10.1083/jcb.202503080）展示了Caenorhabditiselegans中保守的polo样激酶PLK-1如何以意想不到的方式被重新利用，以确保在卵子发生过程中精确的减数分裂染色体分离。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Cell Biology 生物-细胞生物学

CiteScore

12.60

自引率

2.60%

发文量

213

审稿时长

1 months

期刊介绍： The Journal of Cell Biology (JCB) is a comprehensive journal dedicated to publishing original discoveries across all realms of cell biology. We invite papers presenting novel cellular or molecular advancements in various domains of basic cell biology, along with applied cell biology research in diverse systems such as immunology, neurobiology, metabolism, virology, developmental biology, and plant biology. We enthusiastically welcome submissions showcasing significant findings of interest to cell biologists, irrespective of the experimental approach.