{"title":"Is HA0-Mediated heat resistance in influenza a food safety concern? A methodological critique","authors":"Nader Ebrahimi, Sanaz Sadeh, Amir Ghaemi","doi":"10.1016/j.virol.2025.110643","DOIUrl":null,"url":null,"abstract":"<div><div>We have read with interest the recent article by Zhirnov and Chernyshova, it addressed the stability of influenza A virus particles with uncleaved hemagglutinin (HA0) and its possible implication for food safety. While the article addresses an interesting topic, we would like to highlight several methodological and interpretative issues that, in our view, undermine the importance of the conclusions drawn.</div></div>","PeriodicalId":23666,"journal":{"name":"Virology","volume":"611 ","pages":"Article 110643"},"PeriodicalIF":2.4000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Virology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0042682225002569","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
We have read with interest the recent article by Zhirnov and Chernyshova, it addressed the stability of influenza A virus particles with uncleaved hemagglutinin (HA0) and its possible implication for food safety. While the article addresses an interesting topic, we would like to highlight several methodological and interpretative issues that, in our view, undermine the importance of the conclusions drawn.
期刊介绍:
Launched in 1955, Virology is a broad and inclusive journal that welcomes submissions on all aspects of virology including plant, animal, microbial and human viruses. The journal publishes basic research as well as pre-clinical and clinical studies of vaccines, anti-viral drugs and their development, anti-viral therapies, and computational studies of virus infections. Any submission that is of broad interest to the community of virologists/vaccinologists and reporting scientifically accurate and valuable research will be considered for publication, including negative findings and multidisciplinary work.Virology is open to reviews, research manuscripts, short communication, registered reports as well as follow-up manuscripts.