Elena Arribas Lopez, Nazanin Zand, Omorogieva Ojo, Tony Kochhar
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引用次数: 0
Abstract
In times of metabolic stress, the demand for nutrients increases, which is essential to prevent delayed healing and development of chronic wounds. This study presents a systematic review and meta-analysis examining the effect of zinc treatment on wound healing. The review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and included data from four electronic data bases. Five clinical trials met the inclusion criteria. The meta-analysis suggested that zinc treatment may be associated with improvements in ulcers healing at the final endpoint MD: 1.41 (95% CI 1.04, 1.92, p = 0.03). Given the limitations of the included studies, a Grading of Recommendations, Assessment, Development and Evaluation assessment indicated a moderate quality of evidence.
在代谢应激时期，对营养物质的需求增加，这对于防止慢性伤口的延迟愈合和发展至关重要。本研究对锌治疗对伤口愈合的影响进行了系统回顾和荟萃分析。该评价遵循系统评价和荟萃分析指南的首选报告项目，并包括来自四个电子数据库的数据。5项临床试验符合纳入标准。荟萃分析表明，锌治疗可能与最终终点溃疡愈合的改善有关：MD: 1.41 （95% CI 1.04, 1.92, p = 0.03）。考虑到纳入研究的局限性，推荐、评估、发展和评价的分级评估表明证据质量中等。
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