Artificial intelligence: a new era in prostate cancer diagnosis and treatment.

IF 5.2 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Nithin Vidiyala, Prashanth Parupathi, Pavani Sunkishala, Chetan Sree Muppavarapu, Aditya Gujja, Praneeth Kanagala, Sai Krishna Meduri, Dinesh Nyavanandi
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引用次数: 0

Abstract

Prostate cancer (PCa) represents one of the most prevalent cancers among men, with substantial challenges in timely and accurate diagnosis and subsequent treatment. Traditional diagnosis and treatment methods for PCa, such as prostate-specific antigen (PSA) biomarker detection, digital rectal examination, imaging (CT/MRI) analysis, and biopsy histopathological examination, suffer from limitations such as a lack of specificity, generation of false positives or negatives, and difficulty in handling large data, leading to overdiagnosis and overtreatment. The integration of artificial intelligence (AI) in PCa diagnosis and treatment is revolutionizing traditional approaches by offering advanced tools for early detection, personalized treatment planning, and patient management. AI technologies, especially machine learning and deep learning, improve diagnostic accuracy and treatment planning. The AI algorithms analyze imaging data, like MRI and ultrasound, to identify cancerous lesions effectively with great precision. In addition, AI algorithms enhance risk assessment and prognosis by combining clinical, genomic, and imaging data. This leads to more tailored treatment strategies, enabling informed decisions about active surveillance, surgery, or new therapies, thereby improving quality of life while reducing unnecessary diagnoses and treatments. This review examines current AI applications in PCa care, focusing on their transformative impact on diagnosis and treatment planning while recognizing potential challenges. It also outlines expected improvements in diagnosis through AI-integrated systems and decision support tools for healthcare teams. The findings highlight AI's potential to enhance clinical outcomes, operational efficiency, and patient-centred care in managing PCa.

人工智能:前列腺癌诊断和治疗的新时代
前列腺癌(PCa)是男性中最常见的癌症之一,在及时准确的诊断和后续治疗方面面临着巨大的挑战。前列腺特异性抗原(PSA)生物标志物检测、直肠指检、影像学(CT/MRI)分析、活检组织病理学检查等传统的前列腺癌诊疗方法存在特异性不足、易产生假阳性或阴性、大数据处理困难等局限性,导致过度诊断和过度治疗。人工智能(AI)在PCa诊断和治疗中的集成,通过提供早期检测、个性化治疗计划和患者管理的先进工具,正在彻底改变传统方法。人工智能技术,特别是机器学习和深度学习,提高了诊断准确性和治疗计划。人工智能算法分析成像数据,如MRI和超声波,以非常精确的方式有效识别癌症病变。此外,人工智能算法通过结合临床、基因组和成像数据来增强风险评估和预后。这导致了更有针对性的治疗策略,使人们能够在主动监测、手术或新疗法方面做出明智的决定,从而提高生活质量,同时减少不必要的诊断和治疗。本文回顾了目前人工智能在PCa护理中的应用,重点关注它们对诊断和治疗计划的变革性影响,同时认识到潜在的挑战。它还概述了通过人工智能集成系统和医疗团队决策支持工具在诊断方面的预期改进。研究结果强调了人工智能在管理PCa方面提高临床结果、操作效率和以患者为中心的护理方面的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
10.70
自引率
8.60%
发文量
951
审稿时长
72 days
期刊介绍: The International Journal of Pharmaceutics is the third most cited journal in the "Pharmacy & Pharmacology" category out of 366 journals, being the true home for pharmaceutical scientists concerned with the physical, chemical and biological properties of devices and delivery systems for drugs, vaccines and biologicals, including their design, manufacture and evaluation. This includes evaluation of the properties of drugs, excipients such as surfactants and polymers and novel materials. The journal has special sections on pharmaceutical nanotechnology and personalized medicines, and publishes research papers, reviews, commentaries and letters to the editor as well as special issues.
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