Association between postpartum depression and anaesthesia methods in women undergoing caesarean section: A systematic review and meta-analysis.

IF 6.8 2区 医学 Q1 ANESTHESIOLOGY
Si-Cheng Xie, Chuen-Huei Liu, Yu-Ting Hung
{"title":"Association between postpartum depression and anaesthesia methods in women undergoing caesarean section: A systematic review and meta-analysis.","authors":"Si-Cheng Xie, Chuen-Huei Liu, Yu-Ting Hung","doi":"10.1097/EJA.0000000000002252","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Postpartum depression impacts maternal health, child development, and overall family well being. General anaesthesia has been suggested as a potential risk factor.</p><p><strong>Objective: </strong>To assess the association between anaesthetic methods and postpartum depression in women undergoing Caesarean section.</p><p><strong>Design: </strong>Systematic review with meta-analysis.</p><p><strong>Data sources: </strong>We searched PubMed, Embase and Web of Science through 16 April 2025, and included seven studies comprising 1 482 355 patients.</p><p><strong>Eligibility criteria: </strong>Randomised controlled trials and cohort studies comparing postpartum depression outcomes in women undergoing Caesarean section with general anaesthesia versus non-general anaesthesia.</p><p><strong>Results: </strong>Our results showed that general anaesthesia significantly increased the risk of both overall postpartum depression [odds ratio (OR) = 1.64, 95% confidence interval (CI), 1.23 to 2.19] and severe postpartum depression (OR = 1.41, 95% CI, 1.35 to 1.47). Subgroup analysis stratified by timing of postpartum depression diagnosis revealed an elevated risk within one-year postpartum (OR = 1.22, 95% CI, 1.02 to 1.46) and an even higher risk within seven-day postpartum (OR = 4.68, 95% CI, 1.21 to 18.09).</p><p><strong>Conclusion: </strong>These findings highlight the importance of anaesthetic choices for Caesarean section and suggest that minimising general anaesthesia exposure may optimise both physical and mental health outcomes.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":""},"PeriodicalIF":6.8000,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Anaesthesiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/EJA.0000000000002252","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Postpartum depression impacts maternal health, child development, and overall family well being. General anaesthesia has been suggested as a potential risk factor.

Objective: To assess the association between anaesthetic methods and postpartum depression in women undergoing Caesarean section.

Design: Systematic review with meta-analysis.

Data sources: We searched PubMed, Embase and Web of Science through 16 April 2025, and included seven studies comprising 1 482 355 patients.

Eligibility criteria: Randomised controlled trials and cohort studies comparing postpartum depression outcomes in women undergoing Caesarean section with general anaesthesia versus non-general anaesthesia.

Results: Our results showed that general anaesthesia significantly increased the risk of both overall postpartum depression [odds ratio (OR) = 1.64, 95% confidence interval (CI), 1.23 to 2.19] and severe postpartum depression (OR = 1.41, 95% CI, 1.35 to 1.47). Subgroup analysis stratified by timing of postpartum depression diagnosis revealed an elevated risk within one-year postpartum (OR = 1.22, 95% CI, 1.02 to 1.46) and an even higher risk within seven-day postpartum (OR = 4.68, 95% CI, 1.21 to 18.09).

Conclusion: These findings highlight the importance of anaesthetic choices for Caesarean section and suggest that minimising general anaesthesia exposure may optimise both physical and mental health outcomes.

剖宫产妇女产后抑郁与麻醉方式的关系:一项系统综述和荟萃分析。
背景:产后抑郁症影响产妇健康、儿童发育和整体家庭幸福。全身麻醉被认为是一个潜在的危险因素。目的:探讨剖宫产术中麻醉方式与产后抑郁的关系。设计:采用荟萃分析的系统评价。数据来源:截至2025年4月16日,我们检索了PubMed、Embase和Web of Science,纳入了7项研究,包括1482 355名患者。入选标准:随机对照试验和队列研究,比较全麻和非全麻剖宫产妇女产后抑郁症的结局。结果:我们的研究结果显示,全身麻醉显著增加了整体产后抑郁[比值比(OR) = 1.64, 95%可信区间(CI), 1.23 ~ 2.19]和重度产后抑郁(OR = 1.41, 95% CI, 1.35 ~ 1.47)的风险。按产后抑郁症诊断时间分层的亚组分析显示,产后一年内的风险增加(OR = 1.22, 95% CI, 1.02 ~ 1.46),产后7天的风险更高(OR = 4.68, 95% CI, 1.21 ~ 18.09)。结论:这些发现强调了剖宫产麻醉选择的重要性,并提示最小化全身麻醉暴露可以优化身心健康结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
6.90
自引率
11.10%
发文量
351
审稿时长
6-12 weeks
期刊介绍: The European Journal of Anaesthesiology (EJA) publishes original work of high scientific quality in the field of anaesthesiology, pain, emergency medicine and intensive care. Preference is given to experimental work or clinical observation in man, and to laboratory work of clinical relevance. The journal also publishes commissioned reviews by an authority, editorials, invited commentaries, special articles, pro and con debates, and short reports (correspondences, case reports, short reports of clinical studies).
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信