{"title":"Updated and Comprehensive Review of Myristica fragrans Houtt.: Culinary to Cure.","authors":"Nazneen Aiman Siddiqui, Zaib Zarrin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Despite adding flavour, colour, and aroma to cuisine, herbs and spices offer various health benefits. Research over the past decade has enhanced the growing popularity of traditional herbs due to recognition of a diverse range of pharmacological and therapeutic properties. Myristica fragrans (Nutmeg) (Jozbawa/Joz ut teeb) belongs to the family Myristicaceae. It is an aromatic evergreen tree with a peculiar smell, indigenous to the Moluccas, or Spice Islands, Banda Island. Its various part embraces healing values, particularly the bark of the tree is traditionally employed in cardiac disease, viz. hyperlipidaemia, atherosclerosis. The therapeutic uses of nutmeg in other systemic ailments are also described in Unani classical literature.</p><p><strong>Results: </strong>Apart from its traditional uses, pre-clinical and clinical claims exist for significant biological and therapeutic activities such as anti-microbial, hypolipidemic, anti-inflammatory, anti-oxidant, and anti-diabetic on account of identified bioactive constituents including essential oils, phenolic compounds, resins, and pigments in crude extract and various other solvents.</p><p><strong>Conclusion: </strong>This review article aims to analyse and comprehensively summarize the existing ethno-botanical actions and evidence-based claims of traditional uses. However, more research is needed to explore its molecular mechanisms, newer pharmacological and therapeutic activities along with their responsible phytoconstituents, side effects, and hence presents a research gap.</p><p><strong>Keywords: </strong>Myristica fragrans, Nutmeg, anti-inflammatory, myristicin, Unani system of medicine.</p>","PeriodicalId":7571,"journal":{"name":"Alternative therapies in health and medicine","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alternative therapies in health and medicine","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Despite adding flavour, colour, and aroma to cuisine, herbs and spices offer various health benefits. Research over the past decade has enhanced the growing popularity of traditional herbs due to recognition of a diverse range of pharmacological and therapeutic properties. Myristica fragrans (Nutmeg) (Jozbawa/Joz ut teeb) belongs to the family Myristicaceae. It is an aromatic evergreen tree with a peculiar smell, indigenous to the Moluccas, or Spice Islands, Banda Island. Its various part embraces healing values, particularly the bark of the tree is traditionally employed in cardiac disease, viz. hyperlipidaemia, atherosclerosis. The therapeutic uses of nutmeg in other systemic ailments are also described in Unani classical literature.
Results: Apart from its traditional uses, pre-clinical and clinical claims exist for significant biological and therapeutic activities such as anti-microbial, hypolipidemic, anti-inflammatory, anti-oxidant, and anti-diabetic on account of identified bioactive constituents including essential oils, phenolic compounds, resins, and pigments in crude extract and various other solvents.
Conclusion: This review article aims to analyse and comprehensively summarize the existing ethno-botanical actions and evidence-based claims of traditional uses. However, more research is needed to explore its molecular mechanisms, newer pharmacological and therapeutic activities along with their responsible phytoconstituents, side effects, and hence presents a research gap.
Keywords: Myristica fragrans, Nutmeg, anti-inflammatory, myristicin, Unani system of medicine.
背景：除了为菜肴增添风味、颜色和香气外，草药和香料还提供各种健康益处。过去十年的研究已经增强了传统草药的日益普及，由于认识到各种药理和治疗特性。肉豆蔻（Myristica fragrans） （Jozbawa/Joz ut teeb）属于肉豆蔻科。它是一种芳香的常青树，有一种独特的气味，原产于摩鹿加群岛，或香料群岛，班达岛。它的各个部分具有治疗价值，特别是树皮传统上用于心脏病，即高脂血症，动脉粥样硬化。在其他系统性疾病中，肉豆蔻的治疗用途也在Unani经典文献中有所描述。结果：除传统用途外，其在临床前和临床中具有重要的生物和治疗活性，如抗微生物、降血脂、抗炎、抗氧化和抗糖尿病，这是由于其在粗提取物和各种其他溶剂中发现的生物活性成分，包括精油、酚类化合物、树脂和色素。结论：本文旨在分析和全面总结现有的民族植物作用和传统用途的循证主张。然而，其分子机制、药理和治疗活性及其相关植物成分、毒副作用等方面的研究还有待进一步深入，存在研究空白。关键词：肉豆蔻；抗炎；肉豆蔻素；
期刊介绍：
Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field.
Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.
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