{"title":"Role of Phytoestrogens in Gynecological Disorders from the Lens of Unani System of Medicine-A Review.","authors":"Aniya Afaq Khan, Ismath Shameem, Umer Hamid Wani","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>In recent years, there has been a surge of interest in alternative and natural techniques for preventing and treating gynecological disorders. Numerous studies have focused on exploring treatments that have less adverse impact than standard hormonal treatment. Although the etiopathogenetic processes of many gynecological illnesses, such as endometriosis and uterine fibroids, remain unclear, the significance of steroid hormones is undeniable. Endometriosis, uterine leiomyomas, ovarian cancer, and breast cancer all exhibit significant hormonal imbalances. The Unani system of medicine, referred to as Greco-Arabic medicine, is a popular form of traditional medicine widely practiced in many countries. This system utilizes herbs rich in phytoestrogens, which bear structural similarity to 17β-estradiol, and thus have the potential to mimic its estrogenic activity and produce responses. This makes phytoestrogens a suitable substitute for conventional hormonal replacement therapy (HRT) with fewer side effects. Therefore, a comprehensive search for studies on phytoestrogens was conducted using electronic databases such as Google Scholar, ResearchGate, Science Direct, EMBASE, and PubMed. All the relevant literature on gynecological disorders in Unani medicine has been evaluated, assessed, and analyzed based on classical texts. This narrative review summarizes the literature on the physiological role of estrogens and the several potential health benefits of phytoestrogens, with particular attention to the possible role of phytoestrogens in gynecological disorders.</p><p><strong>Keywords: </strong>Phytoestrogens, Gynecological Disorders, Unani Medicine, Hormonal Replacement Therapy, Estrogen, Selective Estrogen Receptor Modulator.</p>","PeriodicalId":7571,"journal":{"name":"Alternative therapies in health and medicine","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alternative therapies in health and medicine","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: In recent years, there has been a surge of interest in alternative and natural techniques for preventing and treating gynecological disorders. Numerous studies have focused on exploring treatments that have less adverse impact than standard hormonal treatment. Although the etiopathogenetic processes of many gynecological illnesses, such as endometriosis and uterine fibroids, remain unclear, the significance of steroid hormones is undeniable. Endometriosis, uterine leiomyomas, ovarian cancer, and breast cancer all exhibit significant hormonal imbalances. The Unani system of medicine, referred to as Greco-Arabic medicine, is a popular form of traditional medicine widely practiced in many countries. This system utilizes herbs rich in phytoestrogens, which bear structural similarity to 17β-estradiol, and thus have the potential to mimic its estrogenic activity and produce responses. This makes phytoestrogens a suitable substitute for conventional hormonal replacement therapy (HRT) with fewer side effects. Therefore, a comprehensive search for studies on phytoestrogens was conducted using electronic databases such as Google Scholar, ResearchGate, Science Direct, EMBASE, and PubMed. All the relevant literature on gynecological disorders in Unani medicine has been evaluated, assessed, and analyzed based on classical texts. This narrative review summarizes the literature on the physiological role of estrogens and the several potential health benefits of phytoestrogens, with particular attention to the possible role of phytoestrogens in gynecological disorders.
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Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field.
Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.
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