Hamed Mortazavi, Anita Taheri, Sara Alehossein, Mehdi Hashemi
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引用次数: 0
Abstract
Introduction: Metastasis to the temporomandibular joint is an uncommon clinical entity that often mimics benign temporomandibular disorders, leading to diagnostic challenges. This systematic review aimed to consolidate the existing literature on temporomandibular joint metastasis to delineate its clinical and demographic characteristics, diagnostic pitfalls, and treatment approaches.
Methods: A comprehensive search was conducted across PubMed/MEDLINE, Scopus, and Embase electronic databases. Two independent reviewers screened the titles, abstracts, and full texts of 3,659 articles, ultimately selecting 47 articles encompassing 55 reported cases.
Results: The analysis revealed a mean patient age of 61.8 ± 13.99 years, with a slight female predominance. Lung and breast cancers were the most common primary sites, with adenocarcinoma being the predominant histopathological type. Clinically, pain, swelling, and restricted mouth opening were the most frequently observed symptoms, although a subset of patients presented with atypical features. Notably, in 49% of cases, TMJ metastasis was detected prior to the diagnosis of the primary malignancy. Multimodal treatment, incorporating combinations of chemotherapy, radiotherapy, and surgery, was the most common therapeutic approach.
期刊介绍:
Saudi Dental Journal is an English language, peer-reviewed scholarly publication in the area of dentistry. Saudi Dental Journal publishes original research and reviews on, but not limited to: • dental disease • clinical trials • dental equipment • new and experimental techniques • epidemiology and oral health • restorative dentistry • periodontology • endodontology • prosthodontics • paediatric dentistry • orthodontics and dental education Saudi Dental Journal is the official publication of the Saudi Dental Society and is published by King Saud University in collaboration with Elsevier and is edited by an international group of eminent researchers.