Quantitative analysis of iris surface smoothness in normal population.

IF 3.9 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Scientific Reports Pub Date : 2025-08-05 DOI:10.1038/s41598-025-13964-7

Hanieh Fakhredin, Tahereh Mahmoudi, Soha Nohasfarmaniyeh, Diba Akbarzadeh, Maryam Kasiri, Elias Khalili Pour, Mohammad Zarei

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Abstract

This study aims to establish normative data for the Smoothness Index (SI) of the iris surface using Anterior Segment Optical Coherence Tomography (AS-OCT) in a healthy population. The study included 198 eyes from 99 subjects, 50 female and 49 males. The average age of participants was 46.71 ± 16.25, spanning 18-75 years. AS-OCT imaging was performed on both eyes before and after pupil dilation. The SI was calculated for various meridians of the iris. Participants were healthy individuals with no underlying iris pathologies, normal intraocular pressure, and a refractive error ranging from spherical equivalent (SE) -3.00 to + 3.00 diopters (D). The average SI was found to be 0.812 ± 0.036, with no significant differences between the eyes. The SI increased slightly with age and was higher in undilated pupils compared to dilated pupils. The study found no significant association between sex and the average SI. The normative range of SI across various meridians was established, providing a reference for future research on iris pathologies. This study highlights the SI pattern of normal iris in Iranians, which can be used for comparison in future research on iris pathologies. These findings are to be confirmed in a larger and more heterogeneous population.

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正常人群虹膜表面平滑度的定量分析。

本研究旨在利用前段光学相干断层扫描（AS-OCT）在健康人群中建立虹膜表面平滑指数（SI）的规范性数据。这项研究包括99名受试者的198只眼睛，其中50名女性和49名男性。参与者的平均年龄为46.71±16.25岁，年龄跨度为18-75岁。扩瞳前后对双眼进行AS-OCT成像。计算虹膜各经络的SI。参与者是健康的个体，没有潜在的虹膜病变，眼压正常，屈光不正范围从球面等效(SE) -3.00到+ 3.00屈光度(D)。平均SI为0.812±0.036，两眼间无显著差异。SI随年龄的增长略有增加，未放大瞳孔的SI高于放大瞳孔。研究发现性别和平均SI之间没有明显的联系。建立了各经络SI的规范范围，为今后虹膜病理研究提供参考。本研究突出了伊朗人正常虹膜的SI模式，可用于未来虹膜病理研究的比较。这些发现将在更大的异质人群中得到证实。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Scientific Reports Natural Science Disciplines-

CiteScore

7.50

自引率

4.30%

发文量

19567

审稿时长

3.9 months

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