Treatment choice and sexual health outcomes in gay and bisexual men with prostate cancer.

IF 5.8 2区医学 Q1 ONCOLOGY

Prostate Cancer and Prostatic Diseases Pub Date : 2025-08-06 DOI:10.1038/s41391-025-01007-1

Daniel R Dickstein, Alex J Bates, Christopher W Wheldon, Ryan Haggart, Kristine M C Talley, Deborah C Marshall, B R Simon Rosser

引用次数: 0

Abstract

Background: The differential impacts of radical prostatectomy (RP) and external beam radiotherapy (EBRT) on sexual health in gay and bisexual men (GBM) with prostate cancer remain understudied, limiting recommendations incorporating preferred sexual behavior.

Methods: Secondary analysis of Restore-2 compared outcomes in GBM after RP (n = 127) or EBRT (n = 27).

Results: Compared to RP, EBRT was associated with lower rates of climacturia (11% vs. 59%, p < 0.001), condom-related erectile dysfunction (27% vs. 51%, p = 0.047), and decreased penile length/girth (49% vs. 69%, p = 0.07), but higher rates of anodyspareunia (33% vs. 14%, p = 0.06).

Conclusions: Exploratory findings suggest EBRT for insertive intercourse, RP for receptive intercourse.

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男同性恋和双性恋前列腺癌患者的治疗选择和性健康结果

背景：根治性前列腺切除术（RP）和外束放疗（EBRT）对患有前列腺癌的男同性恋和双性恋男性（GBM）性健康的不同影响仍未得到充分研究，限制了纳入偏好性行为的建议。方法：二次分析Restore-2比较RP （n = 127）和EBRT （n = 27）后GBM的预后。结果：与RP相比，EBRT与较低的性高潮发生率相关（11%对59%）。结论：探索性发现表明EBRT适用于插入性性交，RP适用于接受性性交。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Prostate Cancer and Prostatic Diseases 医学-泌尿学与肾脏学

CiteScore

10.00

自引率

6.20%

发文量

142

审稿时长

6-12 weeks

期刊介绍： Prostate Cancer and Prostatic Diseases covers all aspects of prostatic diseases, in particular prostate cancer, the subject of intensive basic and clinical research world-wide. The journal also reports on exciting new developments being made in diagnosis, surgery, radiotherapy, drug discovery and medical management. Prostate Cancer and Prostatic Diseases is of interest to surgeons, oncologists and clinicians treating patients and to those involved in research into diseases of the prostate. The journal covers the three main areas - prostate cancer, male LUTS and prostatitis. Prostate Cancer and Prostatic Diseases publishes original research articles, reviews, topical comment and critical appraisals of scientific meetings and the latest books. The journal also contains a calendar of forthcoming scientific meetings. The Editors and a distinguished Editorial Board ensure that submitted articles receive fast and efficient attention and are refereed to the highest possible scientific standard. A fast track system is available for topical articles of particular significance.