{"title":"Tropical gastrointestinal infections of contemporary public health importance.","authors":"Carlos Seas, Pedro Legua","doi":"10.1097/QCO.0000000000001142","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Several gastrointestinal diseases have emerged in the recent decade, representing significant public health problems in the tropics. We aim to review advances in the epidemiology, diagnosis, and treatment of cholera, typhoid fever, and parasitic diseases.</p><p><strong>Recent findings: </strong>Cholera cases are increasing each year, yet few vaccines are available to prevent it. Simplifying single-dose regimens of oral vaccines is promising. Typhoid fever incidence and mortality rates are decreasing, but antibiotic resistance is rising. Typhoid conjugate vaccines are the most efficacious, but several issues remain unsolved regarding their implementation.</p><p><strong>Summary: </strong>Despite better epidemiological tools, diagnostic methods, and therapeutic alternatives, the diarrheal diseases reviewed remain a significant public health problem in the tropics. If a reduction in their burden is aimed at the short- term, investment in water access, sanitation, hygiene, and better vaccines is needed.</p>","PeriodicalId":10880,"journal":{"name":"Current Opinion in Infectious Diseases","volume":" ","pages":"426-432"},"PeriodicalIF":4.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/QCO.0000000000001142","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/6 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: Several gastrointestinal diseases have emerged in the recent decade, representing significant public health problems in the tropics. We aim to review advances in the epidemiology, diagnosis, and treatment of cholera, typhoid fever, and parasitic diseases.
Recent findings: Cholera cases are increasing each year, yet few vaccines are available to prevent it. Simplifying single-dose regimens of oral vaccines is promising. Typhoid fever incidence and mortality rates are decreasing, but antibiotic resistance is rising. Typhoid conjugate vaccines are the most efficacious, but several issues remain unsolved regarding their implementation.
Summary: Despite better epidemiological tools, diagnostic methods, and therapeutic alternatives, the diarrheal diseases reviewed remain a significant public health problem in the tropics. If a reduction in their burden is aimed at the short- term, investment in water access, sanitation, hygiene, and better vaccines is needed.
期刊介绍：
This reader-friendly, bimonthly resource provides a powerful, broad-based perspective on the most important advances from throughout the world literature. Featuring renowned guest editors and focusing exclusively on two topics, every issue of Current Opinion in Infectious Disease delivers unvarnished, expert assessments of developments from the previous year. Insightful editorials and on-the-mark invited reviews cover key subjects such as HIV infection and AIDS; skin and soft tissue infections; respiratory infections; paediatric and neonatal infections; gastrointestinal infections; tropical and travel-associated diseases; and antimicrobial agents.
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