Partial Glossectomy in a 2-month-old Infant with Beckwith-Wiedemann Syndrome - A Case Report.

Abstract

Rationale: Beckwith-Wiedemann syndrome (BWS) is a rare genetic disorder characterised by aberrant growth patterns, tumour risk and a wide range of clinical symptoms. This illness necessitates a multidisciplinary strategy to address the metabolic, multi-organ and structural issues of considerable health concern.

Patient concern: A 56-day-old infant presents with macroglossia due to BWS.

Diagnosis: On examination, the infant revealed an enlarged protruded tongue causing difficulty in sleeping, feeding and breathing.

Treatment: The infant underwent a successful anteroposterior keyhole glossectomy, which improved his airway function, eating and overall quality of life. Tongue tissue was carefully excised and anatomically reconstructed to enhance the function.

Outcome: The patient was followed for up to 22 months; the results were acceptable, with the tongue in its normal position, improved breathing and no feeding issues.

Take-away lesson: In this case report, early intervention improved respiratory function, obstructive sleep apnoea/hypopnoea syndrome and encouraged normal growth and development.