Synthesis, Characterization, and Potential Applications of Menthol-Amino Acid Ester Derivatives.

IF 3.3 4区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Applied Biochemistry and Biotechnology Pub Date : 2025-08-06 DOI:10.1007/s12010-025-05336-8

Lolakhon Ettibaeva, Abduaziz Ergashev, Ugilay Abdurakhmanova, Ruhan Benlikaya, Pınar Güner, Alimjan Matchanov

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引用次数: 0

Abstract

This study focuses on the synthesis of menthyl ester derivatives from menthol and various amino acids such as glycine, histidine, and leucine, and their characterization via high-performance liquid chromatography, Fourier-transform infrared (FTIR) spectroscopy, carbon-13 nuclear magnetic resonance (¹³C-NMR) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM) analyses to determine their structural, chemical, and morphological properties. The FTIR and ¹³C-NMR analyses provided detailed information about the molecular structure, confirming the formation of the menthol-amino acid ester derivatives. The XRD and SEM analyses revealed distinct crystal structures and surface morphologies of the menthol and the ester derivatives. Additionally, antimicrobial activity tests were performed to evaluate their effectiveness against various microorganisms. This study highlights the potential of these compounds as promising candidates for innovative applications in antimicrobial therapies and related scientific disciplines.

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薄荷醇-氨基酸酯衍生物的合成、表征及潜在应用。

本研究以薄荷醇和甘氨酸、组氨酸、亮氨酸等多种氨基酸为原料合成了薄荷酯衍生物，并通过高效液相色谱、傅里叶变换红外（FTIR）光谱、碳-13核磁共振（13C-NMR）光谱、x射线衍射（XRD）和扫描电镜（SEM）分析对其进行了表征，确定了其结构、化学和形态特征。FTIR和13C-NMR分析提供了分子结构的详细信息，证实了薄荷-氨基酸酯衍生物的形成。XRD和SEM分析表明，薄荷醇和酯衍生物的晶体结构和表面形貌不同。此外，还进行了抗菌活性试验，以评估其对各种微生物的有效性。这项研究强调了这些化合物在抗菌治疗和相关科学学科的创新应用方面的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Biochemistry and Biotechnology 工程技术-生化与分子生物学

CiteScore

5.70

自引率

6.70%

发文量

460

审稿时长

5.3 months

期刊介绍： This journal is devoted to publishing the highest quality innovative papers in the fields of biochemistry and biotechnology. The typical focus of the journal is to report applications of novel scientific and technological breakthroughs, as well as technological subjects that are still in the proof-of-concept stage. Applied Biochemistry and Biotechnology provides a forum for case studies and practical concepts of biotechnology, utilization, including controls, statistical data analysis, problem descriptions unique to a particular application, and bioprocess economic analyses. The journal publishes reviews deemed of interest to readers, as well as book reviews, meeting and symposia notices, and news items relating to biotechnology in both the industrial and academic communities. In addition, Applied Biochemistry and Biotechnology often publishes lists of patents and publications of special interest to readers.