Successful treatment of ulerythema ophryogenes with pulsed dye laser: a case report.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
AME Case Reports Pub Date : 2025-07-09 eCollection Date: 2025-01-01 DOI:10.21037/acr-24-215
Giuseppe Lodi, Giovanni Cannarozzo, Irene Fusco, Tiziano Zingoni, Elena Campione, Mario Sannino
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Abstract

Background: Ulerythema ophryogenes (UO) is a rare cutaneous disorder characterized by inflammatory keratotic papules that primarily affect the face. This clinical case may enrich and provide an interesting literature overview on the laser therapy for UO, which represents a rare skin illness difficult to treat.

Case description: A 25-year-old female patient having an UO family history and who presented a progressive erythema and confluent horny follicular erythematous papules with areas of alopecia around the lateral third of eyebrows without signs of pitted or atrophic scars, which has been evident since childhood, underwent to a single session of dye laser. She was complaining of discomfort in the involved skin areas. The patient had not been taking any medications prior to laser therapy. The use of anaesthetic was avoided. After only one therapy session of dye laser the result was clinically optimal. A visible reduction in roughness and a partial hair regrowth in the treated area were observed at 2 months follow-up after treatment. The horn plugs were no longer evident, and the erythema had subsided. The hairs had become thicker, darker, and more numerous, covering most of the underlying dermatitis. Following the laser procedure, the patient didn't experience complications or severe adverse reactions.

Conclusions: Pulsed dye laser treatment appears to be a safe and effective treatment for the erythema and alopecia symptoms associated with this refractory condition.

Abstract Image

Abstract Image

脉冲染料激光治疗发疹性红斑1例。
背景:发疹性Ulerythema ophryogenes (UO)是一种罕见的皮肤疾病,其特征是炎症性角化丘疹,主要影响面部。本病例丰富了激光治疗顽固性皮肤疾病的文献,为顽固性皮肤疾病的治疗提供了一个有趣的文献综述。病例描述:一名25岁的女性患者,有UO家族史,表现为进行性红斑和角状滤泡性红斑丘疹,并在眉毛外侧三分之一处有脱发,没有凹陷或萎缩性疤痕的迹象,自童年以来就很明显,接受了一次染料激光治疗。她抱怨受累的皮肤部位不舒服。患者在接受激光治疗前没有服用任何药物。避免使用麻醉剂。仅一次染料激光治疗后,临床效果最佳。在治疗后2个月的随访中,观察到治疗区域的粗糙度和部分头发再生明显减少。角塞不再明显,红斑消退。毛发变得更厚、更黑、更多,覆盖了大部分潜在的皮炎。在激光手术后,患者没有出现并发症或严重的不良反应。结论:脉冲染料激光治疗似乎是一种安全有效的治疗红斑和脱发症状相关的难治性疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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