The global burden of varicella and herpes zoster in adults aged 65 years and older: a comprehensive analysis based on the global burden of disease 2021

IF 3.4 3区医学 Q2 GERIATRICS & GERONTOLOGY

Aging Clinical and Experimental Research Pub Date : 2025-08-04 DOI:10.1007/s40520-025-03142-0

Jiang Li, Zhaofeng Jin, Wei Yang, Meichen Jin, Jun Niu

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Abstract

Background

The global population is aging at an accelerated rate. There is a lack of data on the burden of varicella and herpes zoster in adults aged 65 years and older.

Objective

This study assesses the global burden of varicella and herpes zoster among adults aged 65 and older from 1992 to 2021.

Methods

We used Global Burden of Disease (GBD) 2021 to identify the number and rates of incidence and disability-adjusted life years (DALYs) of varicella and herpes zoster in adults aged 65 and older.

Results

From 1992 to 2021, The age-standardized incidence rate (ASIR) of varicella and herpes zoster increased among adults aged 65 years and older, while the age-standardized death rate (ASDR) decreased. There were differences in the burden of varicella-zoster among adults aged 65 years and older by among sexes, ages, and regions. The health inequalities analysis showed an improvement among countries.

Conclusion

From 1992 to 2021, the global burden of varicella zoster among adults aged 65 and older has changed significantly. The ASIR of varicella and herpes zoster increased, but ASDR decreased. Despite the notable advancement in health equity across countries, the burden persists disproportionately among populations in low-SDI regions.

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65岁及以上成年人水痘和带状疱疹的全球负担：基于2021年全球疾病负担的综合分析

背景：全球人口正在加速老龄化。关于65岁及以上成年人水痘和带状疱疹负担的数据缺乏。目的：本研究评估1992年至2021年65岁及以上成年人水痘和带状疱疹的全球负担。方法：我们使用全球疾病负担（GBD） 2021来确定65岁及以上成年人水痘和带状疱疹的发病率和残疾调整生命年（DALYs）。结果：1992 - 2021年，65岁及以上成人水痘和带状疱疹的年龄标准化发病率（ASIR）上升，年龄标准化死亡率（ASDR）下降。在65岁及以上的成年人中，水痘-带状疱疹的负担在性别、年龄和地区之间存在差异。健康不平等分析显示，各国之间有所改善。结论：从1992年到2021年，65岁及以上成人水痘带状疱疹的全球负担发生了显著变化。水痘和带状疱疹的ASIR升高，ASDR降低。尽管各国在卫生公平方面取得了显著进展，但低sdi地区的人口仍然承受着不成比例的负担。

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来源期刊

Aging Clinical and Experimental Research 医学-老年医学

CiteScore

7.90

自引率

5.00%

发文量

283

审稿时长

1 months

期刊介绍： Aging clinical and experimental research offers a multidisciplinary forum on the progressing field of gerontology and geriatrics. The areas covered by the journal include: biogerontology, neurosciences, epidemiology, clinical gerontology and geriatric assessment, social, economical and behavioral gerontology. “Aging clinical and experimental research” appears bimonthly and publishes review articles, original papers and case reports.