The impact of different types of exercises on echocardiographic parameters and plasma BNP concentrations in working and sports horses

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Equine Veterinary Education Pub Date : 2024-12-23 DOI:10.1111/eve.14095

J. Isović, D. Čamo, T. Mutevelić, R. Ćutuk, A. Zahirović

{"title":"The impact of different types of exercises on echocardiographic parameters and plasma BNP concentrations in working and sports horses","authors":"J. Isović, D. Čamo, T. Mutevelić, R. Ćutuk, A. Zahirović","doi":"10.1111/eve.14095","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Brain natriuretic peptide (BNP) serves as a crucial cardiac biomarker in human and small animal veterinary medicine, yet its role in equine cardiology remains underexplored.</p>\n </section>\n \n <section>\n \n <h3> Objectives</h3>\n \n <p>This study aimed to investigate the influence of different exercise types on BNP concentrations and single brief echocardiographic parameters in two distinct horse populations, while also examining potential correlations between BNP concentrations and echocardiographic variables.</p>\n </section>\n \n <section>\n \n <h3> Study design</h3>\n \n <p>Forty clinically healthy horses, categorised into working and sports groups, underwent exercise testing exercise to their purposes. BNP concentrations were measured using a horse-specific ELISA kit, and brief echocardiographic examinations were conducted 24 h post-exercise.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Blood samples were collected before, after exercises, and at rest to determine plasma BNP concentrations. The brief echocardiographic examinations looked only at M-mode imaging from the right parasternal window, and assessed cardiac chambers and ventricular diameters. BNP concentrations and echocardiographic variables were compared between the two groups.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Exercise did not significantly increase BNP concentrations in either group, with sports horses exhibiting higher basal BNP values (18.0–1973.0 pg/mL) compared to work horses (14.4–1074.5 pg/mL). No significant differences in BNP concentrations were observed between breeds, sexes, or pregnancy statuses. Brief echocardiographic examinations using M-mode imaging from the right parasternal window revealed significant differences in right ventricular dimensions in diastole and relative wall thickness between the groups. A low negative correlation (<i>r</i> = −0.329, <i>p</i> = 0.038) was observed between BNP concentration and fractional shortening.</p>\n </section>\n \n <section>\n \n <h3> Main limitations</h3>\n \n <p>Single pre-exercise blood sampling, brief M-mode echocardiography, and lack of exercise standardisation in the endurance horse group limited assessing high biological variability on BNP concentration and echocardiographic parameters in the tested horses.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Assessing BNP concentrations and echocardiographic parameters during different exercises can be helpful in examining the functional status of the equine cardiovascular system, guiding tailored exercise regimens for optimal equine well-being.</p>\n </section>\n </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 9","pages":"479-489"},"PeriodicalIF":0.8000,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14095","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Equine Veterinary Education","FirstCategoryId":"97","ListUrlMain":"https://beva.onlinelibrary.wiley.com/doi/10.1111/eve.14095","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Brain natriuretic peptide (BNP) serves as a crucial cardiac biomarker in human and small animal veterinary medicine, yet its role in equine cardiology remains underexplored.

Objectives

This study aimed to investigate the influence of different exercise types on BNP concentrations and single brief echocardiographic parameters in two distinct horse populations, while also examining potential correlations between BNP concentrations and echocardiographic variables.

Study design

Forty clinically healthy horses, categorised into working and sports groups, underwent exercise testing exercise to their purposes. BNP concentrations were measured using a horse-specific ELISA kit, and brief echocardiographic examinations were conducted 24 h post-exercise.

Methods

Blood samples were collected before, after exercises, and at rest to determine plasma BNP concentrations. The brief echocardiographic examinations looked only at M-mode imaging from the right parasternal window, and assessed cardiac chambers and ventricular diameters. BNP concentrations and echocardiographic variables were compared between the two groups.

Results

Exercise did not significantly increase BNP concentrations in either group, with sports horses exhibiting higher basal BNP values (18.0–1973.0 pg/mL) compared to work horses (14.4–1074.5 pg/mL). No significant differences in BNP concentrations were observed between breeds, sexes, or pregnancy statuses. Brief echocardiographic examinations using M-mode imaging from the right parasternal window revealed significant differences in right ventricular dimensions in diastole and relative wall thickness between the groups. A low negative correlation (r = −0.329, p = 0.038) was observed between BNP concentration and fractional shortening.

Main limitations

Single pre-exercise blood sampling, brief M-mode echocardiography, and lack of exercise standardisation in the endurance horse group limited assessing high biological variability on BNP concentration and echocardiographic parameters in the tested horses.

Conclusions

Assessing BNP concentrations and echocardiographic parameters during different exercises can be helpful in examining the functional status of the equine cardiovascular system, guiding tailored exercise regimens for optimal equine well-being.

Abstract Image

查看原文本刊更多论文

不同类型运动对工作马和运动马超声心动图参数和血浆BNP浓度的影响

脑利钠肽（BNP）是人类和小动物兽医学中重要的心脏生物标志物，但其在马心脏病学中的作用仍未得到充分研究。本研究旨在探讨不同运动类型对两种不同马种群中BNP浓度和单一简短超声心动图参数的影响，同时研究BNP浓度与超声心动图变量之间的潜在相关性。研究设计40匹临床健康的马，分为工作组和运动组，进行运动测试。使用马特异性ELISA试剂盒测量脑钠肽浓度，并在运动后24小时进行简短的超声心动图检查。方法分别在运动前、运动后和休息时采血，测定血浆BNP浓度。简短的超声心动图检查仅观察右胸骨旁窗的m型成像，并评估心室和心室直径。比较两组间BNP浓度和超声心动图变量。结果运动没有显著增加两组马的BNP浓度，运动马的基础BNP值（18.0-1973.0 pg/mL）高于工作马（14.4-1074.5 pg/mL）。在品种、性别或妊娠状态之间，BNP浓度没有显著差异。右胸骨旁窗m型超声心动图检查显示两组右心室舒张尺寸和相对壁厚有显著差异。BNP浓度与分数缩短呈低负相关（r = - 0.329, p = 0.038）。在耐力马组中，单一的运动前血液采样，简短的m型超声心动图以及缺乏运动标准化限制了对测试马中BNP浓度和超声心动图参数的高生物学变异性的评估。结论评估不同运动过程中BNP浓度和超声心动图参数有助于检查马心血管系统的功能状态，指导量身定制的运动方案，使马获得最佳的健康状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Equine Veterinary Education 农林科学-兽医学

CiteScore

2.40

自引率

22.20%

发文量

132

审稿时长

18-36 weeks

期刊介绍： Equine Veterinary Education (EVE) is the official journal of post-graduate education of both the British Equine Veterinary Association (BEVA) and the American Association of Equine Practitioners (AAEP). Equine Veterinary Education is a monthly, peer-reviewed, subscription-based journal, integrating clinical research papers, review articles and case reports from international sources, covering all aspects of medicine and surgery relating to equids. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of equine medicine and surgery. The educational value of a submitted article is one of the most important criteria that are assessed when deciding whether to accept it for publication. Articles do not necessarily need to contain original or novel information but we welcome submission of this material. The educational value of an article may relate to articles published with it (e.g. a Case Report may not have direct educational value but an associated Clinical Commentary or Review Article published alongside it will enhance the educational value).