Natasha Kim de Oliveira da Fonseca, Elisa Brietzke
{"title":"Ultra-processed foods and dopamine: Parsing complexity beyond observed variability","authors":"Natasha Kim de Oliveira da Fonseca, Elisa Brietzke","doi":"10.1016/j.cmet.2025.06.008","DOIUrl":null,"url":null,"abstract":"<h2>Section snippets</h2><section><section><h2>Main text</h2>The recent study by Darcey et al.<sup>1</sup> offers a thought-provoking contribution to our understanding of how the human brain responds to ultra-processed foods, particularly in relation to striatal dopamine signaling and adiposity. Using a rigorous positron emission tomography (PET) imaging protocol, the authors report high interindividual variability and an absence of significant association between dopaminergic response and body fat. These findings challenge reductionist views of food addiction as a</section></section><section><section><h2>Declaration of interests</h2>The authors declare no competing interests.</section></section>","PeriodicalId":9840,"journal":{"name":"Cell metabolism","volume":"29 1","pages":""},"PeriodicalIF":30.9000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell metabolism","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.cmet.2025.06.008","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
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Abstract
Section snippets
Main text
The recent study by Darcey et al.1 offers a thought-provoking contribution to our understanding of how the human brain responds to ultra-processed foods, particularly in relation to striatal dopamine signaling and adiposity. Using a rigorous positron emission tomography (PET) imaging protocol, the authors report high interindividual variability and an absence of significant association between dopaminergic response and body fat. These findings challenge reductionist views of food addiction as a
期刊介绍:
Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others.
Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.