Nanosilver Gel, as a novel therapeutic approach, ameliorates wound healing in hand injury patients.

IF 3.7 4区医学 Q3 BIOCHEMICAL RESEARCH METHODS

SLAS Technology Pub Date : 2025-08-01 DOI:10.1016/j.slast.2025.100339

Qingyu Wang, Wenyao Zhong, Xingmiao Feng

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引用次数: 0

Abstract

Background: In recent years, nanosilver gel has gained attention due to its excellent antimicrobial properties and wound healing effects. Meanwhile, the comprehensive care model has improved the rehabilitation environment for patients with its holistic and individualized care approach. This study aimed to investigate the promoting effects of nanosilver gel on wound healing in hand injury patients and the intervention effects of the comprehensive care model.

Methods: This study adopted a randomized controlled trial (RCT) design. A total of 120 hand injury patients admitted to the Hand Surgery Department of Beijing Jishuitan Hospital between January 2020 and January 2023 were enrolled and randomly allocated into three groups (n=40 each). The control group (C group) received standard care, experimental group A (Exp A) underwent a comprehensive nursing intervention, and experimental group B (Exp B) received additional nanosilver gel dressing treatment based on the comprehensive nursing protocol. Primary outcome measures included wound healing time, pain intensity (visual analogue scale (VAS) score), functional recovery (grip strength, hand dexterity, and range of motion), and wound healing rate.

Results: Exp group B had notably better outcomes in terms of wound healing time, pain intensity, functional recovery, and wound healing rate versus C group and Exp group A.

Conclusion: This study demonstrates that the combination of nanosilver gel and the comprehensive care model significantly improves wound healing outcomes in hand injury patients, providing a new and effective possibility for the treatment of hand injuries.

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纳米银凝胶作为一种新的治疗方法，改善了手部损伤患者的伤口愈合。

背景：近年来，纳米银凝胶因其优异的抗菌性能和伤口愈合效果而受到人们的关注。同时，综合护理模式以其整体和个性化的护理方式改善了患者的康复环境。本研究旨在探讨纳米银凝胶对手部损伤患者创面愈合的促进作用及综合护理模式的干预效果。方法采用随机对照试验（RCT）设计。选取2020年1月至2023年1月北京积水潭医院手外科收治的120例手部损伤患者，随机分为3组，每组40例。对照组（C组）给予标准护理，实验组A （Exp A）给予综合护理干预，实验组B （Exp B）在综合护理方案的基础上给予纳米银凝胶敷料治疗。主要结局指标包括伤口愈合时间、疼痛强度（视觉模拟量表（VAS）评分）、功能恢复（握力、手灵活性和活动范围）和伤口愈合率。结果：Exp B组在创面愈合时间、疼痛强度、功能恢复、创面愈合率等方面均明显优于C组和Exp a组。结论：本研究表明纳米银凝胶联合综合护理模式显著改善了手外伤患者创面愈合效果，为手外伤治疗提供了新的有效可能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

SLAS Technology Computer Science-Computer Science Applications

CiteScore

6.30

自引率

7.40%

发文量

审稿时长

106 days

期刊介绍： SLAS Technology emphasizes scientific and technical advances that enable and improve life sciences research and development; drug-delivery; diagnostics; biomedical and molecular imaging; and personalized and precision medicine. This includes high-throughput and other laboratory automation technologies; micro/nanotechnologies; analytical, separation and quantitative techniques; synthetic chemistry and biology; informatics (data analysis, statistics, bio, genomic and chemoinformatics); and more.