Voriconazole-induced photosensitivity and cheilitis.

IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL

Journal of the Royal College of Physicians of Edinburgh Pub Date : 2025-09-01 Epub Date: 2025-08-04 DOI:10.1177/14782715251365359

Mrinal Kanti Das, Krishna Deb Barman, Ananya Sharma

引用次数: 0

Abstract

We present the case of a middle-aged man with orbital and maxillary invasive aspergillosis on treatment with oral voriconazole, who presented with photosensitivity, cracked lips and dark-brown hyperpigmentation of face, upper chest and trunk after 4 months of treatment. Photosensitvity occurs in 10%-20% of patients on treatment with voriconazole, and may even lead to cutaneous malignancies. Patient education about the phototoxic effects of voriconazole is essential at the outset of therapy.

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伏立康唑诱导的光敏性和唇炎。

我们报告一例中年男性患者，经口服伏立康唑治疗后出现眼窝及上颌侵袭性曲霉病，治疗4个月后出现光敏、唇裂、面部、上胸部及躯干黑褐色色素沉着。10%-20%接受伏立康唑治疗的患者出现光敏，甚至可能导致皮肤恶性肿瘤。在治疗开始时，对患者进行伏立康唑光毒性作用的教育是必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Royal College of Physicians of Edinburgh MEDICINE, GENERAL & INTERNAL-

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： The Journal of the Royal College of Physicians of Edinburgh (JRCPE) is the College’s quarterly, peer-reviewed journal, with an international circulation of 8,000. It has three main emphases – clinical medicine, education and medical history. The online JRCPE provides full access to the contents of the print journal and has a number of additional features including advance online publication of recently accepted papers, an online archive, online-only papers, online symposia abstracts, and a series of topic-specific supplements, primarily based on the College’s consensus conferences.