Identifying Responders to Transcatheter Interventions for Secondary Mitral Regurgitation.

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Treatment Options in Cardiovascular Medicine Pub Date : 2025-01-01 Epub Date: 2025-07-31 DOI:10.1007/s11936-025-01095-1

Diane Rizkallah, Carl Ammoury, Elio Haroun, Joseph El Roumi, Ben Alencherry, Rhonda Miyasaka, Amar Krishnaswamy, Samir Kapadia, Serge Harb, Deborah Kwon

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Abstract

Purpose of review: This article offers a comprehensive review of the literature on imaging predictors of response to transcatheter interventions for secondary mitral regurgitation (SMR).

Recent findings: Recent advancements in percutaneous valve therapies have broadened treatment options for high-risk patients with SMR. While recent studies have demonstrated significant reduction in all-cause mortality and hospitalizations with transcatheter edge-to-edge repair (TEER), significant controversy remains. This review highlights the central role of multi-modality imaging to guide therapeutic decision making for optimal treatment response and long-term outcomes.

Summary: Several echocardiographic, computerized tomography (CT) and cardiac magnetic resonance (CMR) imaging parameters are central to identifying optimal conditions for transcatheter therapies. Imaging features have become key predictors of outcomes following transcatheter interventions for secondary mitral regurgitation and provide important risk stratification to guide therapeutic decision making and shared decision making.

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识别经导管介入治疗继发性二尖瓣反流的应答者。

综述目的：本文对经导管介入治疗继发性二尖瓣反流（SMR）反应的影像学预测指标进行了综述。最新发现：经皮瓣膜治疗的最新进展拓宽了高危SMR患者的治疗选择。虽然最近的研究表明，经导管边缘到边缘修复（TEER）可显著降低全因死亡率和住院率，但仍存在重大争议。这篇综述强调了多模态成像在指导治疗决策以获得最佳治疗反应和长期结果方面的核心作用。几个超声心动图、计算机断层扫描（CT）和心脏磁共振（CMR）成像参数是确定经导管治疗最佳条件的核心。影像特征已成为经导管介入治疗继发性二尖瓣反流后预后的关键预测因素，并为指导治疗决策和共同决策提供重要的风险分层。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Treatment Options in Cardiovascular Medicine Medicine-Cardiology and Cardiovascular Medicine

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： This journal aims to review the most important, recently published treatment-related advances in cardiovascular medicine. By providing clear, insightful, balanced contributions by international experts, the journal intends to elucidate novel approaches to treatment in those affected by the spectrum of cardiovascular-related diseases and conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as coronary artery disease, cerebrovascular disease and stroke, heart failure, pediatric and congenital heart disease, and valvular, myocardial, pericardial, and cardiopulmonary diseases. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.