Mehal Rathore, Peter F Reddingius, Peter Campbell, David P Crabb, Pete R Jones
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引用次数: 0
Abstract
Purpose: Glaucoma requires regular visual field (VF) assessments. Eyecatcher 3.0 uses novel "smart glasses" hardware to provide a lightweight, low-cost solution, designed for use while unsupervised. This study aimed to determine the feasibility of using Eyecatcher for VF home-monitoring.
Methods: Eyecatcher 3.0 consists of a smartphone, smart glasses, and wireless clicker. Functionally, it attempts to mimic the Humphrey Field Analyzer (HFA; - same task-instructions, stimuli, and outputs, but smaller field of view and luminance range). Five patients with glaucoma used Eyecatcher to test themselves at home for 3 months (both eyes, monocular, once-per-fortnight). Results from a reduced 24-2 grid were compared to HFA data collected in the clinic, and to normative Eyecatcher data collected from 76 normally sighted young adults. A subset of normally sighted participants (n = 16) also underwent two additional sessions of follow-up testing to assess repeatability. Usability was assessed via questionnaires.
Results: All Eyecatcher tests were completed successfully (100%). There was reasonable agreement with the HFA in terms of mean deviation (MD; r = 0.85, P < 0.001) and observed pattern of loss. The HFA exhibited somewhat better repeatability than Eyecatcher (MD Coefficient of Repeatability = 2.9, 95% confidence interval [CI] = 2.1-4.1 decibels [dB] for HFA, vs. 3.9, 95% CI = 2.8-6.1 dB for Eyecatcher), although this difference was not statistically significant. Average Eyecatcher test duration was 6.5 minutes (both eyes). Patients generally rated the Eyecatcher as easy-to-use, although specific concerns were raised by some individuals.
Conclusions: Smart glasses may provide a feasible means of VFs home-monitoring. Eyecatcher yielded similar sensitivity values to the HFA, and most participants found the lightweight smart glasses acceptable to use. Further research is needed to establish diagnostic accuracy and clinical utility.
Translational relevance: Validation of a new method of glaucoma home monitoring.
期刊介绍:
Translational Vision Science & Technology (TVST), an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders, is an online, open access, peer-reviewed journal emphasizing multidisciplinary research that bridges the gap between basic research and clinical care. A highly qualified and diverse group of Associate Editors and Editorial Board Members is led by Editor-in-Chief Marco Zarbin, MD, PhD, FARVO.
The journal covers a broad spectrum of work, including but not limited to:
Applications of stem cell technology for regenerative medicine,
Development of new animal models of human diseases,
Tissue bioengineering,
Chemical engineering to improve virus-based gene delivery,
Nanotechnology for drug delivery,
Design and synthesis of artificial extracellular matrices,
Development of a true microsurgical operating environment,
Refining data analysis algorithms to improve in vivo imaging technology,
Results of Phase 1 clinical trials,
Reverse translational ("bedside to bench") research.
TVST seeks manuscripts from scientists and clinicians with diverse backgrounds ranging from basic chemistry to ophthalmic surgery that will advance or change the way we understand and/or treat vision-threatening diseases. TVST encourages the use of color, multimedia, hyperlinks, program code and other digital enhancements.