Usefulness and reliability of ¹⁸I-6-β-iodomethyl- norcholesterol (NP-59), adrenal cortex scintigraphy in discrimination between adenoma and hyperplasia in case of a patient with primary hyperaldosteronism (PH) without discontinuation of antihypertension therapy.

IF 1 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Hellenic journal of nuclear medicine Pub Date : 2025-05-01 Epub Date: 2025-08-04 DOI:10.1967/s002449912809

Evangelos Karathanos, Irini Giagourta, Agaristi Kaspiri

引用次数: 0

Abstract

Clear iodine-131 (¹⁸I)-6-β-iodomethyl- norcholesterol aldosterinoma finding, proven on biopsy, without prior discontinuation of spironolactone (due to high blood pressure) reveals no changes on scintigraphic sensitivity.

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18I-6-β-碘甲基-去胆固醇（NP-59），肾上腺皮质显像在原发性醛固酮增多症（PH）患者未停止降压治疗的情况下鉴别腺瘤和增生的有效性和可靠性

明确碘-131 (18I)-6-β-碘甲基-去胆固醇醛固酮瘤的发现，活检证实，没有事先停止使用螺内酯（由于高血压），显示扫描灵敏度没有变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hellenic journal of nuclear medicine 医学-核医学

CiteScore

1.40

自引率

6.70%

发文量

审稿时长

>12 weeks

期刊介绍： The Hellenic Journal of Nuclear Medicine published by the Hellenic Society of Nuclear Medicine in Thessaloniki, aims to contribute to research, to education and cover the scientific and professional interests of physicians, in the field of nuclear medicine and in medicine in general. The journal may publish papers of nuclear medicine and also papers that refer to related subjects as dosimetry, computer science, targeting of gene expression, radioimmunoassay, radiation protection, biology, cell trafficking, related historical brief reviews and other related subjects. Original papers are preferred. The journal may after special agreement publish supplements covering important subjects, dully reviewed and subscripted separately.

Usefulness and reliability of 18I-6-β-iodomethyl- norcholesterol (NP-59), adrenal cortex scintigraphy in discrimination between adenoma and hyperplasia in case of a patient with primary hyperaldosteronism (PH) without discontinuation of antihypertension therapy.

Abstract

Usefulness and reliability of ¹⁸I-6-β-iodomethyl- norcholesterol (NP-59), adrenal cortex scintigraphy in discrimination between adenoma and hyperplasia in case of a patient with primary hyperaldosteronism (PH) without discontinuation of antihypertension therapy.