Oxidation-responsive coacervates composed of oligo(ethylene glycol) bearing benzyl sulfide groups

IF 2.7 4区化学 Q3 POLYMER SCIENCE

Polymer Journal Pub Date : 2025-04-25 DOI:10.1038/s41428-025-01038-4

Ryutaro Fujimoto, Sayuri L. Higashi, Yuki Shintani, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Masato Ikeda

引用次数: 0

Abstract

Herein, we describe the construction of coacervates composed of an oligo(ethylene glycol) derivative bearing benzyl sulfide groups. The obtained liquid-like coacervates (droplets) can undergo oxidation-responsive disassembly through the conversion of the sulfide groups to the sulfoxide groups. Moreover, the coacervates selectively encapsulate hydrophobic molecules; therefore, oxidation-responsive disassembly can lead to the controlled release of the encapsulated molecules. The construction of coacervates composed of an oligo(ethylene glycol) derivative bearing benzyl sulfide groups is presented. The obtained liquid-like coacervates (droplets) can undergo oxidation-responsive disassembly through the conversion of the sulfide groups to the sulfoxide groups. Moreover, the coacervates selectively encapsulate hydrophobic molecules; therefore, oxidation-responsive disassembly can lead to the controlled release of the encapsulated molecules.

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含苯硫醚基团的低聚乙二醇组成的氧化反应性凝聚体

在这里，我们描述了一个低聚（乙二醇）衍生物组成的凝聚体的结构含有苄基硫化物基团。所得到的液体状凝聚体（液滴）可以通过硫化物基团转化为亚砜基团进行氧化反应性分解。此外，凝聚体选择性地包裹疏水分子；因此，氧化反应性分解可以导致被封装分子的可控释放。介绍了含苄基硫化物的低聚（乙二醇）衍生物组成的凝聚体的构造。所得到的液体状凝聚体（液滴）可以通过硫化物基团转化为亚砜基团进行氧化反应性分解。此外，凝聚体选择性地包裹疏水分子；因此，氧化反应性分解可以导致被封装分子的可控释放。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polymer Journal 化学-高分子科学

CiteScore

5.60

自引率

7.10%

发文量

131

审稿时长

2.5 months

期刊介绍： Polymer Journal promotes research from all aspects of polymer science from anywhere in the world and aims to provide an integrated platform for scientific communication that assists the advancement of polymer science and related fields. The journal publishes Original Articles, Notes, Short Communications and Reviews. Subject areas and topics of particular interest within the journal''s scope include, but are not limited to, those listed below: Polymer synthesis and reactions Polymer structures Physical properties of polymers Polymer surface and interfaces Functional polymers Supramolecular polymers Self-assembled materials Biopolymers and bio-related polymer materials Polymer engineering.