Small-for-gestational-age and eating problems in infants aged 2.5 years: a nationwide population-based study in Japan

IF 2.1 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Early human development Pub Date : 2025-11-01 Epub Date: 2025-08-05 DOI:10.1016/j.earlhumdev.2025.106352

Akihito Takeuchi , Naomi Matsumoto , Yousuke Higuchi , Asami Ohyama , Kei Tamai , Kazue Nakamura , Makoto Nakamura , Misao Kageyama , Takashi Yorifuji

{"title":"Small-for-gestational-age and eating problems in infants aged 2.5 years: a nationwide population-based study in Japan","authors":"Akihito Takeuchi , Naomi Matsumoto , Yousuke Higuchi , Asami Ohyama , Kei Tamai , Kazue Nakamura , Makoto Nakamura , Misao Kageyama , Takashi Yorifuji","doi":"10.1016/j.earlhumdev.2025.106352","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To examine the association between small-for-gestational-age (SGA) status and eating behaviors in infants.</div></div><div><h3>Methods</h3><div>Data from a large nationwide population-based longitudinal survey in Japan that began in 2010 was analyzed. The study participants were preterm and term children aged 2.5 years with information on eating behaviors (n = 32,096). SGA was defined as birth weight below the 10th percentile for GA, based on the Japanese reference value for birth size. Poisson regression was used to estimate the risk ratios (RRs) and 95 % confidence intervals (CIs) for the associations between SGA status and each eating problems at 2.5 years of age, adjusting for potential infant- and parent-related confounding factors.</div></div><div><h3>Results</h3><div>SGA children were more likely to have a small appetite (aRR: 2.08, 95 % CI: 1.86–2.32) and fluctuating appetite (aRR: 1.09, 95 % CI: 1.04–1.14), and were more likely to be unable to eat calmly (aRR 1.10, 95 % CI:1.05–1.15) than non-SGA children after controlling for potential confounding variables.</div></div><div><h3>Conclusions</h3><div>SGA was a risk factor for appetite and behavioral problems during eating. For SGA children who are prone to difficulties with eating behavior, a multifaceted approach should be taken to help them improve.</div></div>","PeriodicalId":11435,"journal":{"name":"Early human development","volume":"210 ","pages":"Article 106352"},"PeriodicalIF":2.1000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Early human development","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0378378225001628","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/8/5 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

To examine the association between small-for-gestational-age (SGA) status and eating behaviors in infants.

Methods

Data from a large nationwide population-based longitudinal survey in Japan that began in 2010 was analyzed. The study participants were preterm and term children aged 2.5 years with information on eating behaviors (n = 32,096). SGA was defined as birth weight below the 10th percentile for GA, based on the Japanese reference value for birth size. Poisson regression was used to estimate the risk ratios (RRs) and 95 % confidence intervals (CIs) for the associations between SGA status and each eating problems at 2.5 years of age, adjusting for potential infant- and parent-related confounding factors.

Results

SGA children were more likely to have a small appetite (aRR: 2.08, 95 % CI: 1.86–2.32) and fluctuating appetite (aRR: 1.09, 95 % CI: 1.04–1.14), and were more likely to be unable to eat calmly (aRR 1.10, 95 % CI:1.05–1.15) than non-SGA children after controlling for potential confounding variables.

Conclusions

SGA was a risk factor for appetite and behavioral problems during eating. For SGA children who are prone to difficulties with eating behavior, a multifaceted approach should be taken to help them improve.

查看原文本刊更多论文

2.5岁婴儿的小胎龄和饮食问题：日本一项基于全国人口的研究

目的探讨婴儿小胎龄（SGA）状况与饮食行为的关系。方法对2010年开始的日本全国人口纵向调查数据进行分析。该研究的参与者是2.5岁的早产儿和足月儿童，他们有饮食行为的信息（n = 32,096）。SGA被定义为出生体重低于GA的第10百分位，基于日本出生尺寸参考值。泊松回归用于估计2.5岁时SGA状态与每种饮食问题之间关联的风险比（rr）和95%置信区间（ci），并对潜在的婴儿和父母相关的混杂因素进行调整。结果控制潜在混杂变量后，ssga患儿更容易出现食欲小（aRR: 2.08, 95% CI: 1.86 ~ 2.32）和食欲波动（aRR: 1.09, 95% CI: 1.04 ~ 1.14），更容易出现无法平静进食（aRR: 1.10, 95% CI:1.05 ~ 1.15）。结论ssga是进食过程中出现食欲和行为问题的危险因素。对于容易出现饮食行为困难的SGA儿童，应采取多方面的方法来帮助他们改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Early human development 医学-妇产科学

CiteScore

4.40

自引率

4.00%

发文量

100

审稿时长

46 days

期刊介绍： Established as an authoritative, highly cited voice on early human development, Early Human Development provides a unique opportunity for researchers and clinicians to bridge the communication gap between disciplines. Creating a forum for the productive exchange of ideas concerning early human growth and development, the journal publishes original research and clinical papers with particular emphasis on the continuum between fetal life and the perinatal period; aspects of postnatal growth influenced by early events; and the safeguarding of the quality of human survival. The first comprehensive and interdisciplinary journal in this area of growing importance, Early Human Development offers pertinent contributions to the following subject areas: Fetology; perinatology; pediatrics; growth and development; obstetrics; reproduction and fertility; epidemiology; behavioural sciences; nutrition and metabolism; teratology; neurology; brain biology; developmental psychology and screening.