Extracellular vesicles in dairy cattle: research progress and prospects for practical applications

IF 6.5 1区农林科学 Q1 Agricultural and Biological Sciences

Journal of Animal Science and Biotechnology Pub Date : 2025-08-04 DOI:10.1186/s40104-025-01242-5

Nan Wang, Boqi Zhang, Juan J. Loor, Chunjin Li, Xu Zhou

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引用次数: 0

Abstract

Intensive dairying has diminished infectious disease resistance in dairy cattle and increased the risk of disorders affecting milk quality and productive life. Development of novel health monitoring technologies, optimization of disease treatment protocols using novel biomarkers, and development of antibiotic substitutes are necessary to further enhance the productivity of dairy cattle. Extracellular vesicles (EVs) are key mediators of cellular communication and are essential for maintaining intracellular homeostasis and regulating various physiological and pathological processes. Establishing a network of mechanisms by which EVs regulate physiological processes in dairy cattle will contribute to the development of new technologies for early disease diagnosis and disease treatment. This review summarizes the molecular characterization and advances in the study of EVs in dairy cattle and focuses on the reported mechanisms of action. Prospects and limitations for the application of EVs in monitoring health status, disease treatment and assisted reproduction are discussed.

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奶牛细胞外囊泡的研究进展及应用前景

集约化的奶业降低了奶牛对传染病的抵抗力，增加了影响牛奶质量和生产寿命的疾病的风险。开发新的健康监测技术、利用新的生物标志物优化疾病治疗方案以及开发抗生素替代品是进一步提高奶牛生产力的必要条件。细胞外囊泡（EVs）是细胞通讯的关键介质，对维持细胞内稳态和调节各种生理和病理过程至关重要。建立ev调控奶牛生理过程的机制网络，将有助于开发疾病早期诊断和治疗新技术。本文综述了ev在奶牛体内的分子特征和研究进展，重点介绍了ev在奶牛体内的作用机制。本文讨论了EVs在健康监测、疾病治疗和辅助生殖等方面的应用前景和局限性。

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来源期刊

Journal of Animal Science and Biotechnology AGRICULTURE, DAIRY & ANIMAL SCIENCE-

CiteScore

9.90

自引率

2.90%

发文量

822

审稿时长

17 weeks

期刊介绍： Journal of Animal Science and Biotechnology is an open access, peer-reviewed journal that encompasses all aspects of animal science and biotechnology. That includes domestic animal production, animal genetics and breeding, animal reproduction and physiology, animal nutrition and biochemistry, feed processing technology and bioevaluation, animal biotechnology, and meat science.