The Peptide Paradox in Pharmacology of Obesity.

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Journal of the Pakistan Medical Association Pub Date : 2025-07-01 DOI:10.47391/JPMA.25-53

Sanjay Kalra, Amandeep Singh, Nitin Kapoor

引用次数: 0

Abstract

Peptide biology is a fascinating subject, and peptide pharmacology even more so. Peptides have multiple bodily functions, including their work as hormones and metabolic modulators. However, certain pharmacodynamic and kinetic properties of peptides used in obesity result in paradoxical outcomes. It is helpful for the treating clinician to be aware of these peptide paradoxes, which not only help in understanding the rationale of using these drugs but also help to explain their differences in clinical actions.

查看原文本刊更多论文

肥胖药理学中的肽悖论。

肽生物学是一门迷人的学科，肽药理学更是如此。肽具有多种身体功能，包括它们作为激素和代谢调节剂的作用。然而，某些用于肥胖的多肽的药效学和动力学特性导致矛盾的结果。这有助于治疗临床医生意识到这些肽悖论，这不仅有助于理解使用这些药物的基本原理，而且有助于解释它们在临床作用上的差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of the Pakistan Medical Association Medicine-General Medicine

CiteScore

1.10

自引率

11.10%

发文量

983

审稿时长

3-6 weeks

期刊介绍： Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.