Vascular age calculation from SCORE2 and SCORE2-OP cardiovascular risk tables.

IF 1.9 Q3 PERIPHERAL VASCULAR DISEASE

Clinica e Investigacion en Arteriosclerosis Pub Date : 2025-08-01 DOI:10.1016/j.arteri.2025.500841

Jose I Cuende, Carlos Guijarro

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引用次数: 0

Abstract

Aims: SCORE2 and SCORE2-OP cardiovascular risk tables were published in 2021 and incorporated into European cardiovascular prevention guidelines, replacing the previous SCORE tables. Since the 2012 version of these guidelines, the concept of vascular age has been included. Although there are vascular age tables derived from SCORE, there are no vascular age tables derived from SCORE2 and SCORE2-OP. The aim of this study is to construct new vascular age tables derived from SCORE2 and SCORE2-OP.

Methods: Based on the data from the SCORE2 and SCORE2-OP risk tables, 8 regressions between age and risk are calculated in baseline conditions for the 8 combinations of sex and cardiovascular risk zones. Another 248 regressions corresponding to the different non-baseline situations are calculated. By equating the risk in each box of the risk tables with the same risk in baseline conditions, the vascular age in each box of the risk tables can be obtained. Regression, determination and intraclass correlation coefficients are calculated to asses adjustment and agreement.

Results: Four vascular age tables have been obtained corresponding to countries with low, moderate, high and very high cardiovascular risk. The concordance in vascular age between the 4 tables is greater than 0.99, thus a universal vascular age table has been constructed. Vascular age does not need calibration unlike absolute risk.

Conclusions: Vascular age tables have been created from the SCORE2 and SCORE2-OP tables. A single vascular age table may be used for all European Countries.

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根据SCORE2和SCORE2- op心血管风险表计算血管年龄。

目的：SCORE2和SCORE2- op心血管风险表于2021年发布，并被纳入欧洲心血管预防指南，取代之前的SCORE表。自2012年版指南以来，血管年龄的概念已被纳入其中。虽然有来自SCORE的血管年龄表，但没有来自SCORE2和SCORE2- op的血管年龄表。本研究的目的是基于SCORE2和SCORE2- op构建新的血管年龄表。方法：根据SCORE2和SCORE2- op风险表的数据，在基线条件下计算8种性别和心血管危险区组合的年龄与风险之间的8个回归。另外计算了248个对应于不同非基线情况的回归。通过将风险表中每个方框中的风险与基线条件下相同的风险相等，可以得到风险表中每个方框中的血管年龄。计算回归、决定和类内相关系数来评估调整和一致性。结果：得到了心血管疾病低、中、高、高危国家的血管年龄表。4个表的血管年龄一致性大于0.99，构建了一个通用的血管年龄表。与绝对风险不同，血管年龄不需要校准。结论：血管年龄表是根据SCORE2和SCORE2- op表创建的。单一血管年龄表可用于所有欧洲国家。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinica e Investigacion en Arteriosclerosis PERIPHERAL VASCULAR DISEASE-

CiteScore

3.20

自引率

6.20%

发文量

审稿时长

40 days

期刊介绍： La publicación idónea para acceder tanto a los últimos originales de investigación como a formación médica continuada sobre la arteriosclerosis y su etiología, epidemiología, fisiopatología, diagnóstico y tratamiento. Además, es la publicación oficial de la Sociedad Española de Arteriosclerosis.