Unexplained fall and fatal head injury: Forensic implications of neurocysticercosis.

IF 1.8
Siva Sai Kumar Pulagura, Rahul Panwar, Raghvendra Singh Shekhawat, Vikrant Verma, Divya Aggarwal, Vinay N Gowda
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Abstract

Neurocysticercosis (NCC) is a common parasitic infection of the central nervous system (CNS) by the larval stage of Taenia solium. We present a case of an unresponsive 32-year-old man who was found outside a steel manufacturing factory, taken to the emergency department by the police, and then declared dead. There were no external injuries apparent at autopsy; however, internal examination revealed a basilar skull fracture, subarachnoid hemorrhage, and multiple cystic lesions in the brain. NCC was confirmed by histopathological examination, which revealed cysticerci at different stages of development with accompanying inflammation and gliosis. The person may have been predisposed to seizures as a result of these histological abnormalities. The existence of underlying neuropathological disorders, such as neurocysticercosis (NCC), is an important finding in the context of unexplained sudden death, even when the precise mechanism of trauma could not be conclusively proven due to the lack of eyewitnesses and limited available investigation details. This case underscores the forensic relevance of NCC in unexplained deaths, especially among migrants from the endemic areas. A comprehensive postmortem examination, including past clinical history, background of migration, crime scene investigation, and histopathological analysis, is needed in such cases to help evaluate all possible contributions to the cause of death.

不明原因的跌倒和致命的头部损伤:神经囊虫病的法医意义。
神经囊虫病(NCC)是一种常见的由猪带绦虫幼虫期引起的中枢神经系统(CNS)寄生虫感染。我们提出了一个32岁的男子,他在一家钢铁制造厂外被发现,被警察带到急诊室,然后被宣布死亡。尸检时没有明显的外伤;然而,内部检查显示颅底骨折,蛛网膜下腔出血,脑内多发囊性病变。组织病理学检查证实NCC,发现不同发展阶段的囊虫,并伴有炎症和胶质瘤。由于这些组织学异常,患者可能易患癫痫发作。存在潜在的神经病理疾病,如神经囊虫病(NCC),在不明原因猝死的背景下是一个重要的发现,即使由于缺乏目击者和有限的调查细节,创伤的确切机制无法得到决定性的证明。这一案例强调了NCC在不明原因死亡中的法医相关性,特别是在来自流行地区的移民中。在这种情况下,需要进行全面的尸检,包括过去的临床病史、移民背景、犯罪现场调查和组织病理学分析,以帮助评估所有可能的死因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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