A rare case of intravascular papillary endothelial hyperplasia (Masson’s tumor) of the penis

Abstract

Intravascular papillary endothelial hyperplasia (IPEH), or Masson’s tumor, is an uncommon, benign vascular lesion that can mimic malignant neoplasms. Although commonly found in the skin and soft tissues, its occurrence in the penis is extremely rare. We report the case of a 51-year-old male who presented with a painless, progressively enlarging penile mass. Imaging suggested a benign etiology, and the patient underwent surgical excision. Histopathological analysis confirmed the diagnosis of Masson’s tumor, revealing papillary endothelial proliferation within a thrombotic background. The postoperative course was uneventful, with satisfactory wound healing and no recurrence at follow-up. While rare, penile Masson’s tumor should be considered in the differential diagnosis of vascular penile lesions to avoid misdiagnosis and overtreatment. Surgical excision remains the definitive treatment, with excellent prognosis.