Functional connectivity-related changes underlying mindfulness meditation for internet gaming disorder: a randomized clinical trial.

Npj mental health research Pub Date : 2025-07-31 DOI:10.1038/s44184-025-00154-6

Xuefeng Xu, Haosen Ni, Huabin Wang, Tongtong Wang, Chang Liu, Xiaolan Song, Guang-Heng Dong

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Abstract

Internet gaming disorder (IGD) is recognized as a mental health issue. Traditional interventions have limitations, but mindfulness meditation (MM) shows promise due to its flexibility and social acceptance. Study 1, fMRI data from 61 IGD patients and 60 healthy controls (HCs) were compared to assess functional connectivity (FC). Study 2- a randomized clinical trial, 80 IGD patients underwent either an MM intervention (twice-weekly for 8 sessions) or progressive muscle relaxation (PMR) as a control (pre-registered-Chinese clinical trial registry, ChiCTR2300075869, September 18, 2023). Study 1 revealed abnormal FC within the executive control network (ECN) and between the ECN and reward network in IGD patients. Study 2 showed that MM enhanced FC within the ECN and frontostriatal pathway. MM refining the coupling between brain regions involved in executive control and reward processing. This enhancement improves top-down control over game craving. These findings suggest that MM can effectively treat IGD.

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网络游戏障碍的正念冥想的功能连接相关变化：一项随机临床试验。

网络游戏障碍（IGD）被认为是一种心理健康问题。传统的干预措施有局限性，但正念冥想（MM）由于其灵活性和社会接受度而显示出希望。研究1，比较61名IGD患者和60名健康对照（hc）的fMRI数据，以评估功能连接（FC）。研究2是一项随机临床试验，80名IGD患者接受MM干预（每周两次，共8次）或渐进式肌肉放松（PMR）作为对照（预注册中国临床试验注册，ChiCTR2300075869, 2023年9月18日）。研究1显示，IGD患者的执行控制网络（ECN）内以及ECN和奖励网络之间存在异常的FC。研究2显示，MM增强了ECN和额纹状体通路内的FC。MM细化了涉及执行控制和奖励处理的大脑区域之间的耦合。这种增强增强了对游戏渴望的自上而下的控制。这些结果提示MM能有效治疗IGD。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Npj mental health research

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