Gluteal Muscle Metastasis of Papillary Thyroid Cancer with Increased Somatostatin Receptor Expression in ⁶⁸Ga-DOTATATE PET/MRI.

IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Molecular Imaging and Radionuclide Therapy Pub Date : 2025-10-08 Epub Date: 2025-08-01 DOI:10.4274/mirt.galenos.2025.89847

Ali Kibar, Sertaç Asa, Lebriz Uslu-Beşli, Mine Önenerk, Sait Sağer, Kerim Sönmezoğlu, Haluk Burçak Sayman

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Abstract

A 56-year-old male patient underwent total thyroidectomy, and pathology revealed multicentric papillary thyroid cancer. His post-operative stimulated thyroglobulin value was >500 ng/mL. ¹⁸F-fluorodeoxyglucose positron emission tomography (PET) computed tomography revealed hypermetabolic metastatic pulmonary nodules, cervical, and mediastinal lymph nodes. There was also a hypermetabolic lesion in the left gluteal muscle. Due to the patient's history of a pilonidal cyst in the same region, the possibility of an abscess was also considered, and due to the absence of radioactive iodine (RAI) uptake in the lesion, follow-up was deemed appropriate. During follow-up, as the patient progressed to RAI-refractory state, ⁶⁸Ga-DOTATATE PET/magnetic resonance imaging, which was done for radionuclide therapy planning, revealed heterogeneously increased uptake in the gluteal lesion. A subsequent biopsy confirmed the diagnosis of PTC metastasis.

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68Ga-DOTATATE PET/MRI显示生长抑素受体表达增高的甲状腺乳头状癌臀肌转移。

56岁男性患者行甲状腺全切除术，病理显示多中心乳头状甲状腺癌。术后刺激甲状腺球蛋白值为50 ~ 500 ng/mL。18f -氟脱氧葡萄糖正电子发射断层扫描（PET）计算机断层扫描显示高代谢转移性肺结节，颈部和纵隔淋巴结。左臀肌也有高代谢病变。由于患者在同一区域有毛鞘囊肿病史，因此也考虑了脓肿的可能性，并且由于病变中没有放射性碘（RAI）摄取，因此认为随访是适当的。在随访期间，随着患者进展到rai -难治性状态，68Ga-DOTATATE PET/磁共振成像（用于放射性核素治疗计划）显示臀病变部位摄取不均匀增加。随后的活检证实了甲状腺癌转移的诊断。

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来源期刊

Molecular Imaging and Radionuclide Therapy RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.30

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0.00%

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期刊介绍： Molecular Imaging and Radionuclide Therapy (Mol Imaging Radionucl Ther, MIRT) is publishes original research articles, invited reviews, editorials, short communications, letters, consensus statements, guidelines and case reports with a literature review on the topic, in the field of molecular imaging, multimodality imaging, nuclear medicine, radionuclide therapy, radiopharmacy, medical physics, dosimetry and radiobiology.