Efficacy assessment of the new MWHI blue light technology against relevant healthcare-associated microbial pathogens.

IF 3.2 3区 生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Sara Ramos, Elisabete Ricardo, Pedro O Corda, Acacio Gonçalves Rodrigues, Luis Cobrado
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引用次数: 0

Abstract

Background: The importance of the hospital environment as a source of nosocomial pathogens and, therefore, potentially lethal healthcare-associated infections, has motivated the search for improved high-efficacy no-touch disinfection technologies. Multi-Wavelength High-Intensity (MWHI) blue light is an innovative environmental disinfection system that has already been used for cleanrooms, laboratories, and healthcare facilities.

Aim: The main objective of this study was to assess the efficacy of distinct MWHI blue light exposure cycles against a wide range of healthcare-associated pathogens, grown on different hospital surface and equipment materials.

Methods and results: MWHI disinfection technology was used against ESKAPE pathogens and three distinct Candida species inoculated on five different surface materials frequently used in healthcare settings: formica, linoleum, inox, PVC and napa leather. Four exposure cycles were tested. Colony forming units (CFUs) counts were determined before light exposure (T0) and at each timepoint using contact plates. This technology resulted in a significant reduction of relevant healthcare-associated pathogens grown on multiple surfaces. Pseudomonas aeruginosa exhibited a mean 100% growth reduction after 120 minutes of exposure and Staphylococcus epidermidis a mean growth reduction of 91% after 60 minutes of exposure, highest among gram-positive bacteria (across all materials).

Conclusion: MWHI blue light technology effectively reduced survival of common healthcare-associated pathogens across various surface materials. Considering its safety profile for continuous use, this technology promotes environmental decontamination and, when combined with manual cleaning, significantly reduces microbial burden in healthcare settings.

新型MWHI蓝光技术对相关卫生保健相关微生物病原体的疗效评估
背景:医院环境作为医院病原体来源的重要性,因此,潜在致命的医疗保健相关感染,促使人们寻求改进的高效无接触消毒技术。多波长高强度(MWHI)蓝光是一种创新的环境消毒系统,已用于洁净室、实验室和医疗保健设施。目的:本研究的主要目的是评估不同MWHI蓝光暴露周期对在不同医院表面和设备材料上生长的各种医疗保健相关病原体的功效。方法和结果:MWHI消毒技术对ESKAPE病原体和三种不同的念珠菌种接种在五种不同的表面材料上,在卫生保健环境中经常使用:胶木、油毡、inox、PVC和纳帕皮革。测试了四个暴露周期。在光照前(T0)和每个时间点使用接触板测定菌落形成单位(cfu)计数。这项技术显著减少了在多个表面上生长的与医疗保健相关的病原体。铜绿假单胞菌暴露120分钟后平均生长减少100%,表皮葡萄球菌暴露60分钟后平均生长减少91%,是革兰氏阳性细菌中最高的(在所有材料中)。结论:MWHI蓝光技术可有效降低各种表面材料中常见医疗相关病原体的存活率。考虑到其连续使用的安全性,该技术促进了环境净化,并且与人工清洁相结合,可显着减少医疗保健环境中的微生物负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Applied Microbiology
Journal of Applied Microbiology 生物-生物工程与应用微生物
CiteScore
7.30
自引率
2.50%
发文量
427
审稿时长
2.7 months
期刊介绍: Journal of & Letters in Applied Microbiology are two of the flagship research journals of the Society for Applied Microbiology (SfAM). For more than 75 years they have been publishing top quality research and reviews in the broad field of applied microbiology. The journals are provided to all SfAM members as well as having a global online readership totalling more than 500,000 downloads per year in more than 200 countries. Submitting authors can expect fast decision and publication times, averaging 33 days to first decision and 34 days from acceptance to online publication. There are no page charges.
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