Elizabeth R Hughes, Maria E Panzetta, Agastya Sharma, Raphael H Valdivia
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引用次数: 0
Abstract
Members of the genus Akkermansia are the only known representatives of Verrucomicrobiota within the gastrointestinal tract. Akkermansia muciniphila, the best-characterized representative of the genus, is a mucin-degrading specialist that has emerged as a microbe of significant interest due to its influence on the health of its hosts. We describe emerging themes in the biology of Akkermansia species, including their diversity; cellular structures; physiology; interactions with other intestinal microbes; responses to diet; and effects on mammalian hosts, particularly their role in modulating immune responses. We also describe some of the tools available to explore the molecular biology of Akkermansia and discuss its increasingly complex interactions with other members of the microbiota and their implications for gastrointestinal health.
期刊介绍：
Annual Review of Microbiology is a Medical and Microbiology Journal and published by Annual Reviews Inc. The Annual Review of Microbiology, in publication since 1947, covers significant developments in the field of microbiology, encompassing bacteria, archaea, viruses, and unicellular eukaryotes. The current volume of this journal has been converted from gated to open access through Annual Reviews' Subscribe to Open program, with all articles published under a CC BY license. The Impact Factor of Annual Review of Microbiology is 10.242 (2024) Impact factor. The Annual Review of Microbiology Journal is Indexed with Pubmed, Scopus, UGC (University Grants Commission).
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